期刊
SENSORS AND ACTUATORS B-CHEMICAL
卷 251, 期 -, 页码 902-908出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2017.05.150
关键词
1,8-naphthalimide; Fluorescent probe; Cysteine; Bioimaging
资金
- Priority Academic Program Development of Jiangsu Higher Education Institutions of China
A new fluorescent probe (ABPA) based on 1,8-naphthalimide, which designed on the receptor(1)-fluorophore-spacer-receptor(2) model and employed conjugated addition/cyclization sequence mechanism for Cys detection was reported. The probe shows high selectivity and sensitivity for cysteine (Cys) over other amino acids including the similar structured homocysteine (Hcy) and glutathione (GSH). It displays a highly sensitive fluorescence emission to Cys with a detection limit of 0.12 mu M (S/N = 3), which is far below the normal level of Cys (30-200 mu M) in living cells. Furthermore, ABPA was successfully applied to bioimage intracellular Cys in living cells with low cytotoxicity. (C) 2017 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据