期刊
SENSORS AND ACTUATORS B-CHEMICAL
卷 247, 期 -, 页码 46-52出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2017.02.157
关键词
Indolizine; Bioimaging; ICT; Fluorescent probe
资金
- National Natural Science Foundation of China [21602153]
- Taishan Medical University [2013GCC02]
A simple pH fluorescent probe based on new fluorophore indolizine derivative has been synthesized and characterized. This probe responds to acidic pH (pKa = 3.85) with high quantum yield (phi = 0.52), short response time (within 1 min), high selectivity and sensitivity. The response mechanism of the fluorescent probes relies on ICT changes. The probe was successfully used to monitor intracellular H+ within RAW 264.7 cells. (C) 2017 Elsevier B.V. All rights reserved.
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