Nanoparticles-assembled NiO nanosheets templated by graphene oxide film for highly sensitive non-enzymatic glucose sensing

Nanoparticles-assembled NiO nanosheets have been successfully prepared using graphene oxide (GO) film as template, where the Ni2+ ion was firstly adsorbed in GO film, followed by calcination in N-2 to form NiO-based materials and calcination in air to remove carbon-based template. The morphology, structure, and electrochemical activities of these NiO nanosheets were characterized by X-ray diffraction (XRD), transmission electron microscope (TEM) and electrochemical techniques, respectively. It is found that the NiO nanosheets thus obtained could electrochemically catalyze glucose oxidation in 0.1 M NaOH, leading to fabrication of non-enzymatic glucose sensor. The glucose sensor based on NiO nanosheets exhibits detection limit of 0.18 mu M, and linear range from 1 mu M to 0.4 mM with the sensitivity of 1138 mu AmM-2 cm(-2). Furthermore, such glucose sensor also shows excellent selectivity for detection of glucose, compared to the commonly interfering species, such as ascorbic acid, dopamine, and uric acid. (C) 2016 Elsevier B.V. All rights reserved.