Modification of a polyaniline nano-structured surface for selective cell behaviour

Cellular mobility is one of the key factors that must be studied to understand the intracellular environment and intracellular mechanisms. To achieve this, various methods using micro/nano fabrication technology have been attempted. However, there are many restrictions, depending on materials, substrates, and situations. In this study, we modified surfaces readily by exploiting the mechanical fragility of nanostructures. This method is applicable to various substrates for bioengineering applications. It can also be used to modify a surface while growing cells, allowing for in situ patterning. The surface will affect cellular co-culture and tissue engineering by controlling cellular mobility. (C) 2017 Published by Elsevier B.V.