A schiff-base dual emission ratiometric fluorescent chemosensor for Hg2+ ions and its application in cellular imaging

A schiff-base dual emission ratiometric fluorescent chemosensor which includes coumarin dye and 5-aminoisophthalic acid methyl ester has been designed and synthesized. The chemosensor CA high selectively detects Hg2+ ions in the presence of other biologically important and environmentally relevant metal ions at physiological pH. The double bond of schiff-base was broken accompanied by fluorescence enhancement when the chemosensor interacts with Hg2+ ions, and the coumarin aldehyde and 5-aminoisophthalic acid methyl ester shows strong ratiometric fluorescent emission respectively. And the chemosensor could be applied in cellular imaging at nano molarity by dual fluorescent emission. (C) 2017 Published by Elsevier B.V.