期刊
ENDOCRINOLOGY
卷 159, 期 2, 页码 1188-1198出版社
OXFORD UNIV PRESS INC
DOI: 10.1210/en.2017-03082
关键词
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资金
- Indian Council of Medical Research
- Department of Science and Technology
- Department of Biotechnology, Government of India
Contrary to widespread belief, the implantation of an embryo for the initiation of pregnancy is like a battle, in that the embryo uses a variety of coercive tactics to force its acceptance by the endometrium. We propose that embryo implantation involves a three-step process: (1) identification of a receptive endometrium; (2) superimposition of a blastocyst-derived signature onto the receptive endometrium before implantation; and finally (3) breaching by the embryo and trophoblast invasion, culminating in decidualization and placentation. We review here the story that is beginning to emerge, focusing primarily on the cells that are in combat during this process.
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