期刊
SCHWEIZER ARCHIV FUR TIERHEILKUNDE
卷 159, 期 2, 页码 117-121出版社
GESELLSCHAFT SCHWEIZER TIERARZTINNEN & TIERARZTE
DOI: 10.17236/sat00106
关键词
antibacterial activity; honey-based membranes; multidrug-resistant bacteria; wound infection
In this study, membranes composed of honey (Manuka or Honeydew) and pectin were developed, and the ISO 22196 method was used to evaluate their antibacterial activities against multidrug-resistant bacteria (i.e., Staphylococcus pseudointermedius, Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa) that cause wound infection in animals. The results demonstrated that both Manuka and Honeydew honey-based membranes had strong antibacterial activities against the strain of methicillin-resistant S. pseudointermedius tested. Specifically, membranes composed of Manuka honey were effective in inhibiting the growth of Gram-negative bacteria within 3 h, whereas those composed of Honeydew honey needed 24 h to neutralise bacterial growth. The antimicrobial activities of both membranes developed in this study suggest that they can be effectively used as wound dressing in veterinary clinical medicine.
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