期刊
ARCHIVES OF PHARMACAL RESEARCH
卷 41, 期 2, 页码 184-191出版社
PHARMACEUTICAL SOC KOREA
DOI: 10.1007/s12272-017-0928-8
关键词
Coral; Halotolerant fungus; Aspergillus ochraceus; Antibacterial activity; Aluminum chelates
资金
- National Natural Science Foundation of China [41376148, 81373298, U1501221, 81561148012, U1406402-1]
- Special Fund for Marine Scientific Research in the Public Interest of China [201405038]
Five new pyrazin-2(1H)-one derivatives, ochramides A-D (1-4) and ochralate A (5), as well as three known analogues (6-8) were isolated from the fermentation broth of the marine coral-derived halotolerant Aspergillus ochraceus LCJ11-102 in a nutrient-limited medium containing 10% NaI. Their chemical structures were determined by analyzing NMR and X-ray diffraction data. Compounds 2, 5 and 6 showed antimicrobial activities against Enterobacter aerogenes with the MIC values of 40.0, 18.9, and 20.1 mu M, respectively.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据