期刊
RHEUMATOLOGY
卷 56, 期 -, 页码 100-113出版社
OXFORD UNIV PRESS
DOI: 10.1093/rheumatology/kew417
关键词
biological therapies; systemic lupus erythematosus and autoimmunity; B cells; immunotherapy; clinical trials and methods
类别
This review summarizes traditional and emerging therapies for SLE. Evidence suggests that the heterogeneity of SLE is a crucial aspect contributing to the failure of large clinical trials for new targeted therapies. A clearer understanding of the mechanisms driving disease pathogenesis combined with recent advances in medical science are predicted to enable accelerated progress towards improved SLE diagnosis and personalized approaches to treatment.
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