期刊
MICROORGANISMS
卷 6, 期 1, 页码 -出版社
MDPI
DOI: 10.3390/microorganisms6010022
关键词
brain-gut axis; mycobiome; microbiome; dysbiosis; neurological disorders; psychiatric disorders; fungus
类别
资金
- Hospital of Bordeaux
- Biocodex
- Genoscreen Company
- Vaincre La Mucoviscidose [RF20160501626]
In recent years, the gut microbiota has been considered as a full-fledged actor of the gut-brain axis, making it possible to take a new step in understanding the pathophysiology of both neurological and psychiatric diseases. However, most of the studies have been devoted to gut bacterial microbiota, forgetting the non-negligible fungal flora. In this review, we expose how the role of the fungal component in the microbiota-gut-brain axis is legitimate, through its interactions with both the host, especially with the immune system, and the gut bacteria. We also discuss published data that already attest to a role of the mycobiome in the microbiota-gut-brain axis, and the impact of fungi on clinical and therapeutic research.
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