期刊
REVISTA DO INSTITUTO DE MEDICINA TROPICAL DE SAO PAULO
卷 59, 期 -, 页码 -出版社
INST MEDICINA TROPICAL SAO PAULO
DOI: 10.1590/S1678-9946201759009
关键词
Influenza; National Influenza Surveillance Network; Molecular epidemiology; Vaccination strategy; Public health
Compared to previous years, seasonal influenza activity commenced early in Sao Paulo State, Brazil, Southern hemisphere during the 2016 year. In order to investigate the genetic pattern of influenza A(H1N1) pdm09 in the State of Sao Paulo a total of 479 respiratory samples, collected in January by Sentinel Surveillance Units, were screened by real-time RT-PCR. A total of 6 Influenza viruses A(H1N1) pdm09 presenting ct values <= 30 were sequenced following phylogenetic analysis. The present study identified the circulation of the new 6B. 1 subgroup (A/Sao Paulo/10-118/2016 and A/Sao Paulo/3032/2016). In addition, influenza A(H1N1) pdm09 group 6B has also been identified during January in the State of Sao Paulo. Despite amino acid changes and changes in potential glycosylation motifs, 6B. 1 viruses were well inhibited by the reference ferret antiserum against A/California/07/2009 virus, the A(H1N1) pdm09 component of the vaccine for the 2016 influenza season.
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