期刊
ADVANCED SYNTHESIS & CATALYSIS
卷 360, 期 5, 页码 875-880出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adsc.201701323
关键词
Azides; gold catalysis; enynes; hetero-cycles; tandem reaction
资金
- National Natural Science Foundation of China [21372219, 21572225]
A gold(I)/BrOnsted acid-catalyzed cyclization of 2-azidobenzaldehydes with 3-aza-1,6-enynes has been developed for the synthesis of tetrahydrobenzo[b][1,8]naphthyridine derivatives. This protocol enabled the modular synthesis of tetracyclic heterocycles in one operation with water and nitrogen gas as the byproducts.
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