期刊
JOURNAL OF DIABETES INVESTIGATION
卷 9, 期 2, 页码 244-255出版社
WILEY
DOI: 10.1111/jdi.12723
关键词
Biomarker; Diabetic complications; Metabolomics
资金
- National Natural Science Foundation of China [81620108030]
- 3-Year Action Plan of Shanghai Municipal Committee of Health and Family Planning [ZY3-CCCX-2-1002]
- Shanghai Rising-Star Project [15QA1403500]
Diabetes has become a major global health problem. The elucidation of characteristic metabolic alterations during the diabetic progression is critical for better understanding its pathogenesis, and identifying potential biomarkers and drug targets. Metabolomics is a promising tool to reveal the metabolic changes and the underlying mechanism involved in the pathogenesis of diabetic complications. The present review provides an update on the application of metabolomics in diabetic complications, including diabetic coronary artery disease, diabetic nephropathy, diabetic retinopathy and diabetic neuropathy, and this review provides notes on the prevention and prediction of diabetic complications.
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