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Vaginal Microbiomes Associated With Aerobic Vaginitis and Bacterial Vaginosis

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FRONTIERS IN PUBLIC HEALTH
卷 6, 期 -, 页码 -

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FRONTIERS MEDIA SA
DOI: 10.3389/fpubh.2018.00078

关键词

aerobic vaginitis; bacterial vaginosis; vaginal microbiomes; group B Streptococcus; preterm birth

资金

  1. South African National Research Foundation (NRF) as part of the Department of Science and Technology-NRF CAPRISA Centre of Excellence in HIV Prevention at the University of Cape Town

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A healthy vaginal microbiota is considered to be significant for maintaining vaginal health and preventing infections. However, certain vaginal bacterial commensal species serve an important first line of defense of the body. Any disruption of this microbial barrier might result in a number of urogenital conditions including aerobic vaginitis (AV) and bacterial vaginosis (BV). The health of the vagina is closely associated with inhabitant microbiota. Furthermore, these microbes maintain a low vaginal pH, prevent the acquisition of pathogens, stimulate or moderate the local innate immune system, and further protect against complications during pregnancies. Therefore, this review will focus on vaginal microbial health in the lower reproductive tract of women and on the physiological characteristics that determine the well-being of reproductive health. In addition, we explore the distinct versus shared characteristics of BV and AV, which are commonly associated with increased risk for preterm delivery.

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