期刊
REGULATORY TOXICOLOGY AND PHARMACOLOGY
卷 84, 期 -, 页码 94-101出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.yrtph.2017.01.002
关键词
Bioactives; Nutrition; Tolerable upper intake levels; Dietary reference intakes; DRIs; Nutrient reference values; Lutein; Green tea; EGCG; Epigallocatechin gallate
There is increasing interest by consumers, researchers, and regulators into the roles that certain bioactive compounds, derived from plants and other natural sources, can play in health maintenance and promotion, and even prolonging a productive quality of life. Research has rapidly emerged suggesting that a wide range of compounds and mixtures in and from plants (such as fruits and vegetables, tea and cocoa) and animals (such as fish and probiotics) may exert substantial health benefits. There is interest in exploring the possibility of establishing recommended intakes or dietary guidance for certain bioactive substances to help educate consumers. A key aspect of establishing dietary guidance is the assessment of safety/toxicity of these substances. Toxicologists need to be involved in both the development of the safety framework and in the evaluation of the science to establish maximum intake/upper limits. (C) 2017 The Authors. Published by Elsevier Inc.
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