期刊
DERMATO-ENDOCRINOLOGY
卷 9, 期 1, 页码 -出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/19381980.2017.1361576
关键词
Sebaceous gland; endocrinology; cannabinoid; TRP channels; acne
类别
资金
- New National Excellence Program of the Ministry of Human Capacities
- National Research, Development and Innovation Office [120187, 121360, GINOP-2.3.2-15-2016-00050]
- Janos Bolyai research scholarship of the Hungarian Academy of Sciences
The sebaceous gland, long considered an evolutionary relic with little-to-no physiological relevance in humans, has emerged in recent decades as a key orchestrator and contributor to many cutaneous functions. In addition to the classical physico-chemical barrier function of the skin against constant environmental challenges, a more novel, neuro-immune modulatory role has also emerged. As part of the complex intercellular communication network of the integumentary system, the sebaceous gland acts as a relay station in the skin for many endocrine factors. This review aims to offer a comprehensive overview of endocrine effects and subsequent interactions on this much maligned mini-organ.
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