期刊
CHEMOSENSORS
卷 6, 期 1, 页码 -出版社
MDPI
DOI: 10.3390/chemosensors6010005
关键词
Raman spectroscopy; surface-enhanced Raman spectroscopy; bacteria; biofilm; nanoparticles
资金
- Scientific and Technological Research Council of Turkey (TUBITAK Project) [214Z129]
- Yeditepe University
- COST action European Network on Raman-Based Applications for Clinical Diagnostics (Raman4clinics) [BM1401]
Biofilms are a communal way of living for microorganisms in which microorganism cells are surrounded by extracellular polymeric substances (EPS). Most microorganisms can live in biofilm form. Since microorganisms are everywhere, understanding biofilm structure and composition is crucial for making the world a better place to live, not only for humans but also for other living creatures. Raman spectroscopy is a nondestructive technique and provides fingerprint information about an analyte of interest. Surface-enhanced Raman spectroscopy is a form of this technique and provides enhanced scattering of the analyte that is in close vicinity of a nanostructured noble metal surface such as silver or gold. In this review, the applications of both techniques and their combination with other biofilm analysis techniques for characterization of composition and structure of biofilms are discussed.
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