期刊
CEN CASE REPORTS
卷 7, 期 1, 页码 21-23出版社
SPRINGER JAPAN KK
DOI: 10.1007/s13730-017-0284-z
关键词
Hypocalcemia; Secondary hyperparathyroidism; Cinacalcet; Hungry bone syndrome
Cinacalcet is an effective and safe alternative to parathyroidectomy in end stage renal disease (ESRD) patients with secondary hyperparathyroidism. Hypocalcemia is a known complication of treatment that is usually readily reversible upon discontinuation of the drug. It rarely manifests severely and symptomatically requiring hospital admission. We present the case of a 55 year old man with severe, symptomatic and prolonged hypocalcemia that occurred 2 weeks after starting cinacalcet. Cinacalcet induced a state of pharmacological parathyroidectomy with subsequent hungry bone syndrome. Serum calcium returned to normal range after 4 weeks of stopping the drug while receiving high doses of elemental calcium and vitamin D receptor activation therapy (VDRA).
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