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Savina Apolloni et al.
HUMAN MOLECULAR GENETICS (2013)
Signaling through Purinergic Receptors for ATP Induces Human Cutaneous Innate and Adaptive Th17 Responses: Implications in the Pathogenesis of Psoriasis
Meaghan E. Killeen et al.
JOURNAL OF IMMUNOLOGY (2013)
The purinergic 2X7 receptor participates in renal inflammation and injury induced by high-fat diet: possible role of NLRP3 inflammasome activation
Anna Solini et al.
JOURNAL OF PATHOLOGY (2013)
Physiological Roles and Potential Therapeutic Applications of the P2X7 Receptor in Inflammation and Pain
Luiz Anastacio Alves et al.
MOLECULES (2013)
CD73 promotes anthracycline resistance and poor prognosis in triple negative breast cancer
Sherene Loi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Purinergic signalling and cancer
Geoffrey Burnstock et al.
PURINERGIC SIGNALLING (2013)
Purinergic Receptor Antagonist A438079 Protects Against Acetaminophen-Induced Liver Injury by Inhibiting P450 Isoenzymes, Not by Inflammasome Activation
Yuchao Xie et al.
TOXICOLOGICAL SCIENCES (2013)
Motor neuron dysfunction in a mouse model of ALS: Gender-dependent effect of P2X7 antagonism
Chiara Cervetto et al.
TOXICOLOGY (2013)
P2X7 receptor-mediated purinergic signaling promotes liver injury in acetaminophen hepatotoxicity in mice
Rafaz Hoque et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2012)
Extracellular ATP induces cell death in human intestinal epithelial cells
Carolina O. Souza et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2012)
The Neuroprotective Effect of a Specific P2X7 Receptor Antagonist Derives from its Ability to Inhibit Assembly of the NLRP3 Inflammasome in Glial Cells
Niamh Murphy et al.
BRAIN PATHOLOGY (2012)
Effects of genetic variation in the P2RX7 gene on pharmacodynamics of a P2X7 receptor antagonist: a prospective genotyping approach
Simon M. McHugh et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2012)
The role of P2X7 purinergic receptors in inflammatory and nociceptive changes accompanying cyclophosphamide-induced haemorrhagic cystitis in mice
J. P. Martins et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Expression of P2X7 Receptor Increases In Vivo Tumor Growth
Elena Adinolfi et al.
CANCER RESEARCH (2012)
The His155Tyr (489C>T) single nucleotide polymorphism of P2RX7 gene confers an enhanced function of P2X7 receptor in immune cells from patients with rheumatoid arthritis
Liliana Portales-Cervantes et al.
CELLULAR IMMUNOLOGY (2012)
P2X7 Receptors: Channels, Pores and More
C. Volonte et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2012)
Feasibility study of B16 melanoma therapy using oxidized ATP to target purinergic receptor P2X7
Fumie Hattori et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2012)
P2X7 receptor antagonism attenuates the hypertension and renal injury in Dahl salt-sensitive rats
Xu Ji et al.
HYPERTENSION RESEARCH (2012)
Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity
Robert E. Sorge et al.
NATURE MEDICINE (2012)
Efficacy and Safety of Diquafosol Ophthalmic Solution in Patients with Dry Eye Syndrome: A Japanese Phase 2 Clinical Trial
Yukihiro Matsumoto et al.
OPHTHALMOLOGY (2012)
Activation of P2X7 Receptor by ATP Plays an Important Role in Regulating Inflammatory Responses during Acute Viral Infection
Benjamin H. Lee et al.
PLOS ONE (2012)
P2X7 Receptor Signaling in the Pathogenesis of Smoke-Induced Lung Inflammation and Emphysema
Monica Lucattelli et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2011)
Hypoxia-increased RAGE and P2X7R expression regulates tumor cell invasion through phosphorylation of Erk1/2 and Akt and nuclear translocation of NF-κB
Marco Tafani et al.
CARCINOGENESIS (2011)
Anthrax Toxin Induces Macrophage Death by p38 MAPK Inhibition but Leads to Inflammasome Activation via ATP Leakage
Syed Raza Ali et al.
IMMUNITY (2011)
UV-B induced alteration in purinergic receptors and signaling on HaCaT keratinocytes
Olga Ruzsnavszky et al.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2011)
Inhibition of the P2X7 Receptor Reduces Cystogenesis in PKD
Ming-Yang Chang et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2011)
Lipopolysaccharide-induced lung injury: Role of P2X7 receptor
Leonardo C. Moncao-Ribeiro et al.
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY (2011)
European meeting P2 receptors: new targets for the treatment of osteoporosis
Niklas Rye Jorgensen et al.
PURINERGIC SIGNALLING (2011)
Structure-activity relationships and in vivo activity of (1H-pyrazol-4-yl)acetamide antagonists of the P2X7 receptor
Paul J. Beswick et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
AF-353, a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist
Joel R. Gever et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
Functional variants of the P2RX7 gene, aseptic osteolysis, and revision of the total hip arthroplasty:A preliminary study
F. Mrazek et al.
HUMAN IMMUNOLOGY (2010)
Lack of the purinergic receptor P2X7 results in resistance to contact hypersensitivity
Felix C. Weber et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
The effects of P2X7 receptor antagonists on the formation and function of human osteoclasts in vitro
Ankita Agrawal et al.
PURINERGIC SIGNALLING (2010)
Activation of P2X7-mediated apoptosis Inhibits DMBA/TPA-induced formation of skin papillomas and cancer in mice
Wen Fu et al.
BMC CANCER (2009)
Atypical P2X7 receptor pharmacology in two human osteoblast-like cell lines
S. M. Alqallaf et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
P2X7-mediated chemoprevention of epithelial cancers
George I. Gorodeski
EXPERT OPINION ON THERAPEUTIC TARGETS (2009)
Altered P2X7-receptor level and function in mouse models of Huntington's disease and therapeutic efficacy of antagonist administration
Miguel Diaz-Hernandez et al.
FASEB JOURNAL (2009)
Genetics of the P2X7 receptor and human disease
Stephen J. Fuller et al.
PURINERGIC SIGNALLING (2009)
Increased expression of the pro-apoptotic ATP-sensitive P2X7 receptor in experimental and human glomerulonephritis
Clare M. Turner et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2007)
Extracellular ATP has stimulatory effects on the expression and release of IL-6 via purinergic receptors in normal human epidermal keratinocytes
Kaori Inoue et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2007)
Physiology and pathophysiology of purinergic neurotransmission
Geoffrey Burnstock
PHYSIOLOGICAL REVIEWS (2007)
The role of purinergic P2X7 receptors in the inflammation and fibrosis of unilateral ureteral obstruction in mice
R. G. Goncalves et al.
KIDNEY INTERNATIONAL (2006)
Pathophysiology and therapeutic potential of purinergic signaling
G Burnstock
PHARMACOLOGICAL REVIEWS (2006)
P2X7 receptors regulate NKT cells in autoimmune hepatitis
H Kawamura et al.
JOURNAL OF IMMUNOLOGY (2006)
A Thr357 to Ser polymorphism in homozygous and compound heterozygous subjects causes absent or reduced P2X7 function and impairs ATP-induced mycobacterial killing by macrophages
AN Shemon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Early prostate cancer detected using expression of non-functional cytolytic P2X7 receptors
M Slater et al.
HISTOPATHOLOGY (2004)
P2X and P2Y purinoceptor expression in pancreas from streptozotocin-diabetic rats
R Coutinho-Silva et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2003)
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