期刊
CLINICAL ENDOSCOPY
卷 51, 期 3, 页码 266-273出版社
KOREAN SOC GASTROINTESTINAL ENDOSCOPY
DOI: 10.5946/ce.2017.109
关键词
Stomach neoplasms; Endoscopic submucosal dissection; Neoplasms; second primary
Background/Aims: Endoscopic submucosal dissection (ESD) has been widely accepted as a method of treatment of early gastric tumor. 'this study aimed to identify the incidence and characteristics of multiple gastric tumors after ESD. Methods: Patients with early gastric tumors who were treated by ESD from January 2004 to June 2012 and followed up with endoscopic examination periodically for at least 1 year were enrolled. All multiple gastric lesions were subsequently treated with ESD and the medical records of the patients were retrospectively reviewed. Results: In total, 643 patients were included. The mean duration of endoscopic follow-up was 45.27 +/- 27.59 (range, 12-148) months. Overall, 144 patients (22.4%) showed multiple gastric tumors during the follow-up period (44 synchronous [6.8%] and 100 metachronous [15.5%]). The cumulative incidence rate steadily increased during the follow-up period. More than 50% of the tumors that developed at the same longitudinal location of the stomach were of the same macroscopic and histological type as the primary lesions. Conclusions: Because synchronous and/or metachronous gastric tumors are common, considerable attention should be paid to detect multiple gastric lesions after ESD of early gastric neoplasm.
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