期刊
EUROPEAN EATING DISORDERS REVIEW
卷 26, 期 3, 页码 265-271出版社
WILEY
DOI: 10.1002/erv.2580
关键词
anorexia nervosa; biological; neuroimaging; neuropsychology
资金
- NIMH [K23 MH093684]
ObjectiveTo determine if an interpersonal attribution bias associated with self-perception, the externalizing bias, was related to neural activations during mentalization. MethodsA functional magnetic resonance imaging task involving verbal appraisals measured neural activations when thinking about oneself and others in 59 adults, including healthy women as well as women with and recovered from anorexia nervosa. Whole-brain regressions correlated brain function during mentalization with the externalizing bias measured using the Internal, Personal, and Situational Attributions Questionnaire. ResultsWomen with anorexia nervosa had a lower externalizing bias, demonstrating a tendency to self-attribute more negative than positive social interactions, unlike the other groups. The externalizing bias was correlated with activation of the left inferior frontal gyrus and posterior insula, when comparing thinking about others evaluating oneself with direct self-evaluation. DiscussionExternalizing biases may provide an office-based assay reflecting neurocognitive disturbances in social self-perception that are common during anorexia nervosa.
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