期刊
MENOPAUSE REVIEW-PRZEGLAD MENOPAUZALNY
卷 16, 期 2, 页码 51-56出版社
TERMEDIA PUBLISHING HOUSE LTD
DOI: 10.5114/pm.2017.68592
关键词
premature ovarian failure; infertility; menstrual disorders
Premature ovarian failure (POF) is the term usually used to describe women aged younger than 40 years, who present with amenorrhoea, hypergonadotropic hypogonadism, and infertility. POF is a devastating diagnosis for reproductive-aged women. The clinical presentation is diverse, and several different disorders can lead to premature ovarian failure. POF has serious health consequences, including psychological distress, infertility, osteoporosis, autoimmune disorders, ischaemic heart disease, and increased risk of mortality. Hashimoto's disease is the most frequent autoimmune disorder associated with premature ovarian failure. Management should be initiated immediately to prevent long-term consequences. Oestrogen therapy is the mainstay of management. Hormone therapy should be provided to eliminate symptoms of oestrogen deficiency.
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