相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Enhanced Conformational Sampling of N-Glycans in Solution with Replica State Exchange Metadynamics
Raimondas Galvelis et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2017)
Cellular glycosylation affects Herceptin binding and sensitivity of breast cancer cells to doxorubicin and growth factors
Diluka Peiris et al.
SCIENTIFIC REPORTS (2017)
GC1118, an Anti-EGFR Antibody with a Distinct Binding Epitope and Superior Inhibitory Activity against High-Affinity EGFR Ligands
Yangmi Lim et al.
MOLECULAR CANCER THERAPEUTICS (2016)
Molecular basis for multimerization in the activation of the epidermal growth factor receptor
Yongjian Huang et al.
ELIFE (2016)
Activation of transmembrane cell-surface receptors via a common mechanism? The rotation model''
Ichiro N. Maruyama
BIOESSAYS (2015)
N-Glycosylation as determinant of epidermal growth factor receptor conformation in membranes
Karol Kaszuba et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Probing the Binding Mechanism of Mnk Inhibitors by Docking and Molecular Dynamics Simulations
Srinivasaraghavan Kannan et al.
BIOCHEMISTRY (2015)
COSMIC: exploring the world's knowledge of somatic mutations in human cancer
Simon A. Forbes et al.
NUCLEIC ACIDS RESEARCH (2015)
mAb806 binding to epidermal growth factor receptor: a computational study
Yao Zong Ng et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2015)
Activation of the Epidermal Growth Factor Receptor: A Series of Twists and Turns
David Poger et al.
BIOCHEMISTRY (2014)
Membrane Interaction of Bound Ligands Contributes to the Negative Binding Cooperativity of the EGF Receptor
Anton Arkhipov et al.
PLOS COMPUTATIONAL BIOLOGY (2014)
Mechanisms of Activation of Receptor Tyrosine Kinases: Monomers or Dimers
Ichiro N. Maruyama
CELLS (2014)
Architecture and Membrane Interactions of the EGF Receptor
Anton Arkhipov et al.
CELL (2013)
Molecular Determinants of Epidermal Growth Factor Binding: A Molecular Dynamics Study
Jeffrey M. Sanders et al.
PLOS ONE (2013)
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
Yibing Shan et al.
CELL (2012)
MMPBSA.py: An Efficient Program for End-State Free Energy Calculations
Bill R. Miller et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2012)
Free Energy Calculations by the Molecular Mechanics Poisson-Boltzmann Surface Area Method
Nadine Homeyer et al.
MOLECULAR INFORMATICS (2012)
A Two-in-One Antibody against HER3 and EGFR Has Superior Inhibitory Activity Compared with Monospecific Antibodies
Gabriele Schaefer et al.
CANCER CELL (2011)
Assessing the Performance of the MM/PBSA and MM/GBSA Methods. 1. The Accuracy of Binding Free Energy Calculations Based on Molecular Dynamics Simulations
Tingjun Hou et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2011)
Improved Treatment of Ligands and Coupling Effects in Empirical Calculation and Rationalization of pKa Values
Chresten R. Sondergaard et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2011)
Assessing the Performance of the Molecular Mechanics/Poisson Boltzmann Surface Area and Molecular Mechanics/Generalized Born Surface Area Methods. II. The Accuracy of Ranking Poses Generated From Docking
Tingjun Hou et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2011)
Sialylation and fucosylation of epidermal growth factor receptor suppress its dimerization and activation in lung cancer cells
Ying-Chih Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Role of glycosylation in structure and stability of Erythrina corallodendron lectin (EcorL): A molecular dynamics study
Sandeep Kaushik et al.
PROTEIN SCIENCE (2011)
Structural Evidence for Loose Linkage between Ligand Binding and Kinase Activation in the Epidermal Growth Factor Receptor
Chafen Lu et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
A systematic approach to protein glycosylation analysis: a path through the maze
Karina Marino et al.
NATURE CHEMICAL BIOLOGY (2010)
N-glycan of ErbB family plays a crucial role in dimer formation and tumor promotion
Motoko Takahashi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2008)
Matuzumab binding to EGFR prevents the conformational rearrangement required for dimerization
Judith Schmiedel et al.
CANCER CELL (2008)
Structural basis for EGF receptor inhibition by the therapeutic antibody IMC-11F8
Shiqing Li et al.
STRUCTURE (2008)
GLYCAM06: A generalizable Biomolecular force field. Carbohydrates
Karl N. Kirschner et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2008)
Epidermal growth factor receptor tyrosine kinase is modulated by GM3 interaction with N-linked GlcNAc termini of the receptor
Seon-Joo Yoon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Structural model of the mAb 806-EGFR complex using computational docking followed by computational and experimental mutagenesis
A Sivasubramanian et al.
STRUCTURE (2006)
Functional effects of glycosylation at asn-579 of the epidermal growth factor receptor
KB Whitson et al.
BIOCHEMISTRY (2005)
Structural basis for inhibition of the epidermal growth factor receptor by cetuximab
SQ Li et al.
CANCER CELL (2005)
Recent advances in the development and application of implicit solvent models in biomolecule simulations
M Feig et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2004)
STRIDE: a web server for secondary structure assignment from known atomic coordinates of proteins
M Heinig et al.
NUCLEIC ACIDS RESEARCH (2004)
Accelerated molecular dynamics: A promising and efficient simulation method for biomolecules
D Hamelberg et al.
JOURNAL OF CHEMICAL PHYSICS (2004)
Exploring protein native states and large-scale conformational changes with a modified generalized born model
A Onufriev et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2004)
Characterization of glycosylation sites of the epidermal growth factor receptor
YJ Zhen et al.
BIOCHEMISTRY (2003)
EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization
KM Ferguson et al.
MOLECULAR CELL (2003)
Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor α
TPJ Garrett et al.
CELL (2002)
Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains
H Ogiso et al.
CELL (2002)
The Asn-420-linked sugar chain in human epidermal growth factor receptor suppresses ligand-independent spontaneous oligomerization - Possible role of a specific chain in controllable receptor activation
T Tsuda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Characterization of the carbohydrate chains of the secreted form of the human epidermal growth factor receptor
CJM Stroop et al.
GLYCOBIOLOGY (2000)
Characterization of the N-oligosaccharides attached to the atypical Asn-X-Cys sequence of recombinant human epidermal growth factor receptor
C Sato et al.
JOURNAL OF BIOCHEMISTRY (2000)
分享论文
