期刊
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
卷 58, 期 8, 页码 1406-1417出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/10408398.2016.1260526
关键词
Mycotoxins; apoptosis; necrotic cell death; autophagic cell death; p53; MAPKs; endoplasmic reticulum stress; reactive oxygen species
资金
- National Natural Science Foundation of China (NSFC) [31371752, 31401494]
Mycotoxins are secondary metabolites of fungi that contaminate a wide range of foods and feeds. Mycotoxin contamination is considered to be an important risk factor for food safety which poses serious threat to human and animal health. Cell death induction is suggested to be the key cellular event contributed to the pleiotropically toxic effects of mycotoxins. During the past decades, substantial progress has been made in uncovering the mechanisms of cell death induction by mycotoxins. Understanding of the mechanisms underlying mycotoxin-induced cytotoxicity will benefit the development of effective strategies for the management of mycotoxin-associated health issues. The current review will discuss the types of cell death induced by mycotoxins and summarize the present understanding of signaling pathways involved in mycotoxin-mediated cytotoxicities.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据