期刊
JOURNAL OF SCLERODERMA AND RELATED DISORDERS
卷 3, 期 2, 页码 122-131出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/2397198318757699
关键词
Systemic sclerosis; microangiopathy; nailfold videocapillaroscopy; scleroderma patterns; diagnostic tools; connective tissue diseases
类别
资金
- Research Laboratory and Academic Division of Rheumatology of the University of Genova, Italy
Systemic sclerosis is an autoimmune connective tissue disease characterized by early and persistent microvascular impairment which leads to functional and organic manifestations, with progressive fibrosis of the skin and internal organs. Morphological and functional assessment of the peripheral microvasculature is a must, not only for diagnosis but also for the prognosis and therapeutical follow-up of systemic sclerosis patients, as reported in recent studies. Nailfold videocapillaroscopy is the validated technique for the study of scleroderma microangiopathy as it is able to detect peripheral microvascular morphology and both classify and score the capillary abnormalities into different microangiopathy patterns ('Early', 'Active' and 'Late'). Indeed, the possibility to early diagnose and follow the microvascular changes and the safety of the technique have made nailfold videocapillaroscopy a mandatory tool for patient evaluation and included its assessment in the new systemic sclerosis classification criteria. Important links between nailfold videocapillaroscopy patterns and systemic sclerosis clinical manifestations have been described.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据