相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle Kinase 1 (MPS1) Using a Structure-Based Hybridization Approach
Paolo Innocenti et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Novel Mps1 Kinase Inhibitors with Potent Antitumor Activity
Antje M. Wengner et al.
MOLECULAR CANCER THERAPEUTICS (2016)
Discovery of Pyrazolo[1,5-a]pyrimidine TTK Inhibitors: CFI-402257 is a Potent, Selective, Bioavailable Anticancer Agent
Yong Liu et al.
ACS MEDICINAL CHEMISTRY LETTERS (2016)
Combination Approaches with immune-Checkpoint Blockade in Cancer Therapy
Maarten Swart et al.
FRONTIERS IN ONCOLOGY (2016)
Preclinical characterization of the novel TTK kinase inhibitor S81694 for the treatment of triple negative breast cancer
Riccardo Colombo et al.
CANCER RESEARCH (2015)
The Discovery of Orally Bioavailable Tyrosine Threonine Kinase (TTK) Inhibitors: 3-(4-(heterocyclyl)phenyl)-1H-indazole-5-carboxamides as Anticancer Agents
Yong Liu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Targeting Mitosis in Cancer: Emerging Strategies
Carmen Dominguez-Brauer et al.
MOLECULAR CELL (2015)
Mitotic Checkpoint Kinase Mps1 Has a Role in Normal Physiology which Impacts Clinical Utility
Ricardo Martinez et al.
PLOS ONE (2015)
The Interplay of Immunotherapy and Chemotherapy: Harnessing Potential Synergies
Leisha A. Emens et al.
CANCER IMMUNOLOGY RESEARCH (2015)
Functional Characterization of CFI-400945, a Polo-like Kinase 4 Inhibitor, as a Potential Anticancer Agent
Jacqueline M. Mason et al.
CANCER CELL (2014)
Selective Inhibition of Pancreatic Ductal Adenocarcinoma Cell Growth by the Mitotic MPS1 Kinase Inhibitor NMS-P715
Roger B. Slee et al.
MOLECULAR CANCER THERAPEUTICS (2014)
Characterization of novel MPS1 inhibitors with preclinical anticancer activity
M. Jemaa et al.
CELL DEATH AND DIFFERENTIATION (2013)
Effects of the Selective MPS1 Inhibitor MPS1-IN-3 on Glioblastoma Sensitivity to Antimitotic Drugs
Bakhos A. Tannous et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2013)
The Spindle Assembly Checkpoint
Pablo Lara-Gonzalez et al.
CURRENT BIOLOGY (2012)
The clonal and mutational evolution spectrum of primary triple-negative breast cancers
Sohrab P. Shah et al.
NATURE (2012)
Characterization of the Cellular and Antitumor Effects of MPI-0479605, a Small-Molecule Inhibitor of the Mitotic Kinase Mps1
Keith D. Tardif et al.
MOLECULAR CANCER THERAPEUTICS (2011)
High levels of the Mps1 checkpoint protein are protective of aneuploidy in breast cancer cells
Jewel Daniel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Phenotypic heterogeneity and instability of human ovarian tumor-initiating cells
Jocelyn M. Stewart et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Targeting the Mitotic Checkpoint for Cancer Therapy with NMS-P715, an Inhibitor of MPS1 Kinase
Riccardo Colombo et al.
CANCER RESEARCH (2010)
Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex
Laura Hewitt et al.
JOURNAL OF CELL BIOLOGY (2010)
Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function
Nicholas Kwiatkowski et al.
NATURE CHEMICAL BIOLOGY (2010)
Pharmacologic Abrogation of the Mitotic Spindle Checkpoint by an Indolocarbazole Discovered by Cellular Screening Efficiently Kills Cancer Cells
Ailine Stolz et al.
CANCER RESEARCH (2009)
Regulation of Kinetochore Recruitment of Two Essential Mitotic Spindle Checkpoint Proteins by Mps1 Phosphorylation
Quanbin Xu et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells
Aniek Janssen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Mps1 kinase activity restrains anaphase during an unperturbed mitosis and targets Mad2 to kinetochores
Anthony Tighe et al.
JOURNAL OF CELL BIOLOGY (2008)
Gene Expression Signature of Cigarette Smoking and Its Role in Lung Adenocarcinoma Development and Survival
Maria Teresa Landi et al.
PLOS ONE (2008)
Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism
Jean-Frangois Maure et al.
CURRENT BIOLOGY (2007)
A cell proliferation and chromosomal instability signature in anaplastic thyroid carcinoma
Giuliana Salvatore et al.
CANCER RESEARCH (2007)
Effects of aneuploidy on cellular physiology and cell division in haploid yeast
Eduardo M. Torres et al.
SCIENCE (2007)
The molecular portraits of breast tumors are conserved across microarray platforms
Zhiyuan Hu et al.
BMC GENOMICS (2006)
Increased expression of mitotic checkpoint genes in breast cancer cells with chromosomal instability
BB Yuan et al.
CLINICAL CANCER RESEARCH (2006)
Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint
A Abrieu et al.
CELL (2001)