期刊
JOURNAL OF EXERCISE REHABILITATION
卷 14, 期 2, 页码 168-174出版社
KOREAN SOC EXERCISE REHABILITATION
DOI: 10.12965/jer.1836070.035
关键词
Low back pain; Obesity; Sedentary lifestyle; C-reactive protein; Prostaglandins
资金
- Capes
- Fapesp [SPRINT 2014/50672-8]
Low back pain is a health issue with significant impact to patients and society. This narrative review aims to synthesize the relationship between obesity, low-grade inflammation and low back pain. It is known that a sedentary lifestyle is a risk factor for obesity and related disorders. The adipose tissue of obese people secretes a range of cytokines of character pro-and anti-inflammatory, with many molecular effects. In addition, pro-inflammatory cytokines are sensitizers of C-reactive protein (CRP), a marker of acute inflammation that can be linked to the musculoskeletal pain sensation individuals with back pain. Another inflammatory marker deserves mention, prostaglandin E-2. Prostaglandin E-2 is important in the process of triggering actions such as pyrexia, sen-sation of pain and inflammation, which are exhibited in low back pain condition. The potential for exercises and physical activity to control these mediators and act as a preventative measure for back pain are important because they work as a nonpharmacological strategy to this target audience. There are two types of exercise discussed in this review, the moderate-intensity continuous training and high-intensity interval training.
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