期刊
CURRENT OBESITY REPORTS
卷 7, 期 2, 页码 122-129出版社
SPRINGER
DOI: 10.1007/s13679-018-0303-1
关键词
Obesity; Food cues; Brain activity hormone; Energy balance
资金
- NIH [K23 DK098286-02, K08-AA023545]
- Brain and Behavior Research Foundation
- National Center for Advancing Translational Science (NCATS), a component of the National Institutes of Health (NIH) [UL1 TR00142]
Purpose of Review In the modern obesogenic environment, food cues play a crucial role in the development of obesity by disrupting hormone and energy balance mechanisms. Thus, it is critical to understand the neurobiology of feeding behaviors and obesity in the context of ubiquitous food cues. The current paper reviews the physiology of feeding, hormonal regulation of energy balance, and food cue responses and discusses their contributions to obesity. Recent Findings Food cues have strong impact on human physiology. Obese individuals have altered food cue-elicited responses in the brain and periphery, overpowering hormone and energy balance regulation. Disrupted homeostasis during food cue exposure leads to continued food intake, unsuccessful weight management, and poor treatment outcomes, which further contributes to obesity epidemic. Summary Findings from the review emphasize the crucial role of food cues in obesity epidemic, which necessitates multidimensional approaches to the prevention and treatment of obesity, including psychosocial interventions to reduce food cue reactivity, along with conventional treatment.
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