期刊
PRIMARY CARE
卷 44, 期 4, 页码 599-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.pop.2017.07.003
关键词
Nonalcoholic fatty liver disease (NAFLD); Nonalcoholic steatohepatitis (NASH); Liver disease; Metabolic disease; Dyslipidemia; Insulin resistance; Steatosis
Nonalcoholic fatty liver disease (NAFLD) defines a condition of hepatic steatosis with or without hepatic injury. NAFLD is increasing in prevalence worldwide and presents a public health burden. Most patients are asymptomatic, although some present with fatigue and right upper quadrant pain. NAFLD is discovered incidentally when patients have elevated liver enzymes or fatty liver is seen on imaging modalities. Imaging studies can confirm fatty deposits in the liver, but needle biopsy is needed to determine the degree of inflammation. The mainstay of treatment is weight loss and controlling diabetes and hyperlipidemia. Liver transplantation is considered when disease progresses to cirrhosis.
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