期刊
POSTHARVEST BIOLOGY AND TECHNOLOGY
卷 134, 期 -, 页码 17-21出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.postharvbio.2017.07.011
关键词
Citrus green mold; Secondary metabolites; Genomic synteny; Pathogen-host interaction
资金
- National Science Foundation of China [31300131, 31371961]
- China Agriculture Research System [CARS-27]
- Hangzhou Normal University [SYSKF201609]
Penicillium digitatum is one of the primary cause agents of postharvest loss of citrus fruits. Although a number of the secondary metabolites (SMs) that it produces have been identified, their biosynthesis pathways and biological roles in infection and decay development have not been fully characterized to date. In the present study, three SM biosynthesis pathways were identified using domain characterization, comparative genomics and co-regulation analysis. These pathways include the tryptoquialanines (TQA) biosynthesis pathway that was up-regulated during fruit infection. Subsequently, a gene knockout mutant was constructed, which revealed that the tqaA gene was involved in TQA production in P. digitatum. However, no significant variation was detected between the non-TQA mutant and the wild-type strain in fungal growth, development, stress responses or pathogenicity. In summary, this study improved the annotation of three SM biosynthesis pathways possibly involved in the infection of citrus hosts by P. digitatum. However, further investigation revealed that one of the products, TQA, was not involved in the interaction between P. digitatum and their citrus hosts.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据