期刊
POLYMER TESTING
卷 63, 期 -, 页码 360-366出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.polymertesting.2017.08.036
关键词
Collagen; Thymol; Bactericidal properties; Biofilm formation
资金
- Faculty of Biology and Environmental Protection, Nicolaus Copernicus University in Torun [2834B]
- National Science Centre (NCN, Poland) [UMO-2013/11/B/ST8/04444]
Recently, special attention has been paid to the development of active wound dressing materials based on biopolymers. Collagen is a natural polymer, which meets the requirements of modern materials for medical applications. However, despite its unique propdrties, collagen has no antimicrobial activity. In this work thymol was incorporated into collagen films to meet antimicrobial properties of the material. Thymol is a naturally occurring phenolic compound recognized as an antimicrobial agent. Collagen/thymol thin films were obtained through solvent evaporation using collagen solutions containing different amounts of thymol. The structure of the obtained materials was studied using FTIR-ATR spectroscopy. The inhibition ability on the growth of several strains of microorganisms was tested. The standard ISO 22196:2007 was used to define the bactericidal properties of the material. The growth of the following bacteria on the collagen/thymol films was studied: Escherichia coil, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis, Enterobacter aerogenes, Candida albicans. The results showed that the growth of Staphylococcus aureus was the most inhibited compared to the other tested strains. Collagen/thymol material is more efficient against pathogens through direct contact compared to the diffusion of thymol from the material. In general, the thymol addition inhibits biofilm formation on the collagen surface. (C) 2017 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据