期刊
MEMBRANES
卷 8, 期 1, 页码 -出版社
MDPI
DOI: 10.3390/membranes8010002
关键词
chitosan-gelatin-ferulic acid blend; ferulic acid crosslinker; hexagonal porous film; biodegradable blend; biomedical film/membrane
In this work, a chitosan-gelatin-ferulic acid blend was used in different ratios for preparing novel films that can be used in biomedical applications. Both acetic and formic acid were tested as solvents for the chitosan-gelatin-ferulic acid blend. Glycerol was tested as a plasticizer. The thickness, mechanical strength, static water contact angle and water uptake of the prepared films were determined. Also, the prepared films were characterized using different analysis techniques such as Fourier transform infrared spectroscopy (FT-IR) analysis, X-ray diffraction (XRD), thermal gravimetric analysis (TGA), differential scanning calorimetry (DSC) and scanning electron microscopy (SEM). Acetic acid produced continuous compact surfaces that are not recommended for testing in biomedical applications. The plasticized chitosan-gelatin-ferulic acid blend, using formic acid solvent, produced novel hexagonal porous films with a pore size of around 10-14 mu m. This blend is recommended for preparing films (scaffolds) for testing in biomedical applications as it has the advantage of a decreased thickness.
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