4.7 Article

Exploring structural effects in single-chain folding mediated by intramolecular thermal Diels-Alder chemistry

期刊

POLYMER CHEMISTRY
卷 8, 期 34, 页码 5120-5128

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c7py00320j

关键词

-

资金

  1. Army Research Office [W911NF-14-1-0177]
  2. NIST [70NANB15H060]

向作者/读者索取更多资源

We describe a method to fold single polymer chains into nanoparticles using simple thermal Diels-Alder (DA) chemistry. Two different folding strategies are explored, one employing chain-internal folding and the other using external, multi-functional cross-linkers. In the first strategy, random terpolymers were designed with varying incorporations of methyl methacrylate (MMA), furfuryl methacrylate (FMA) and a maleimide functionalized methacrylate (MIMA) to achieve internal folding through a thermal DA reaction between pendent furan and maleimide groups. In the second method, the synthesis of random copolymers of MMA and FMA forms nanoparticles after effecting a thermal DA reaction between pendent furan groups and external bi-or tri-maleimide functionalized cross-linkers. This multifaceted approach compares different synthetic designs of linear polymers as well as multiple cross-linker species as a means to explore the effect these synthetic differences have on the resulting SCNP. The two polymer series designed in this study allow for a direct comparison between chain internal cross-linking of multiple internal pendent groups and external cross-linker mediated collapse.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据