期刊
ENTROPY
卷 17, 期 4, 页码 1896-1915出版社
MDPI
DOI: 10.3390/e17041896
关键词
-
资金
- Institute Universitaire de France (IUF)
- Spanish Ministry of Economy and Innovation [DPI2014-51844-C2-1-R]
In this work, we begin by considering the qualitative modeling of biological regulatory systems using process hitting, from which we define its probabilistic counterpart by considering the chemical master equation within a kinetic theory framework. The last equation is efficiently solved by considering a separated representation within the proper generalized decomposition framework that allows circumventing the so-called curse of dimensionality. Finally, model parameters can be added as extra-coordinates in order to obtain a parametric solution of the model.
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