4.3 Article

Three new terpenoids from the Eupatorium chinense

期刊

PHYTOCHEMISTRY LETTERS
卷 20, 期 -, 页码 224-227

出版社

ELSEVIER SCIENCE BV
DOI: 10.1016/j.phytol.2017.04.004

关键词

Eupatorium chinense; Terpenoids; Structural elucidation; Anticancer activity

资金

  1. National Natural Science Foundations of China [21272136, 21272137]
  2. Opening Foundation of the State Key Laboratory of Mycology [SKLMKF201501]
  3. Startup Foundation of China Three Gorges University

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Three new terpenoids compounds (1-3) were obtained from ethyl acetate fraction, which was yielded from Eupatorium chinense's ethanol extract. Their structures were determined on the basis of 1D and 2D NMR spectroscopy, including H-1-H-1 COSY, HMBC, HSQC and NOESY experiments. All of the isolated compounds were tested in vitro for their cytotoxic activities against the HepG(2), HGC-27 and MDA-MB-231 cancer cell lines.

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