相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Loss-of-function genetic tools for animal models: cross-species and cross-platform differences
Benjamin E. Housden et al.
NATURE REVIEWS GENETICS (2017)
Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity
Jin Li et al.
CELL (2017)
Mutations in RIT1 cause Noonan syndrome - additional functional evidence and expanding the clinical phenotype
M. Koenighofer et al.
CLINICAL GENETICS (2016)
Single epicardial cell transcriptome sequencing identifies Caveolin 1 as an essential factor in zebrafish heart regeneration
Jingli Cao et al.
DEVELOPMENT (2016)
FGF1 Mediates Overnutrition-Induced Compensatory β-Cell Differentiation
Mingyu Li et al.
DIABETES (2016)
Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation
Nuala A. O'Leary et al.
NUCLEIC ACIDS RESEARCH (2016)
Leveraging Large-scale Behavioral Profiling in Zebrafish to Explore Neuroactive Polypharmacology
Matthew N. McCarroll et al.
ACS CHEMICAL BIOLOGY (2016)
Zebrafish heart as a model to study the integrative autonomic control of pacemaker function
Matthew R. Stoyek et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2016)
Essential light chain S195 phosphorylation is required for cardiac adaptation under physical stress
Lisa-Mareike Scheid et al.
CARDIOVASCULAR RESEARCH (2016)
Multicolor mapping of the cardiomyocyte proliferation dynamics that construct the atrium
Matthew J. Foglia et al.
DEVELOPMENT (2016)
Real-time 3D visualization of cellular rearrangements during cardiac valve formation
Jenny Pestel et al.
DEVELOPMENT (2016)
Building and re-building the heart by cardiomyocyte proliferation
Matthew J. Foglia et al.
DEVELOPMENT (2016)
Maximizing mutagenesis with solubilized CRISPR-Cas9 ribonucleoprotein complexes
Alexa Burger et al.
DEVELOPMENT (2016)
An insulin signaling feedback loop regulates pancreas progenitor cell differentiation during islet development and regeneration
Lihua Ye et al.
DEVELOPMENTAL BIOLOGY (2016)
Precise Editing of the Zebrafish Genome Made Simple and Efficient
Kazuyuki Hoshijima et al.
DEVELOPMENTAL CELL (2016)
Cell Migration During Heart Regeneration in Zebrafish
Naoyuki Tahara et al.
DEVELOPMENTAL DYNAMICS (2016)
Long-term drug administration in the adult zebrafish using oral gavage for cancer preclinical studies
Michelle Dang et al.
DISEASE MODELS & MECHANISMS (2016)
Pharmacological treatment and BBB-targeted genetic therapy for MCT8-dependent hypomyelination in zebrafish
David Zada et al.
DISEASE MODELS & MECHANISMS (2016)
Ferredoxin 1b (Fdx1b) Is the Essential Mitochondrial Redox Partner for Cortisol Biosynthesis in Zebrafish
Aliesha Griffin et al.
ENDOCRINOLOGY (2016)
Permanent Deiodinase Type 2 Deficiency Strongly Perturbs Zebrafish Development, Growth, and Fertility
Anne M. Houbrechts et al.
ENDOCRINOLOGY (2016)
Phenotype-based Discovery of 2-[(E)-2-(Quinolin-2-yl)vinyl]phenol as a Novel Regulator of Ocular Angiogenesis
Alison L. Reynolds et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015
Mohammad H. Forouzanfar et al.
LANCET (2016)
Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015
Haidong Wang et al.
LANCET (2016)
Tools for automating the imaging of zebrafish larvae
Rock Pulak
METHODS (2016)
Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification
Sven Reischauer et al.
NATURE (2016)
Motor neurons control locomotor circuit function retrogradely via gap junctions
Jianren Song et al.
NATURE (2016)
Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth
Andrew G. Cox et al.
NATURE CELL BIOLOGY (2016)
Zebrafish behavioral profiling identifies multitarget antipsychotic-like compounds
Giancarlo Bruni et al.
NATURE CHEMICAL BIOLOGY (2016)
Long-term glycemic control using polymer-encapsulated human stem cell-derived beta cells in immune-competent mice
Arturo J. Vegas et al.
NATURE MEDICINE (2016)
Leptin signaling regulates glucose homeostasis, but not adipostasis, in the zebrafish
Maximilian Michel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Whole-organism lineage tracing by combinatorial and cumulative genome editing
Aaron McKenna et al.
SCIENCE (2016)
Recent advancements in understanding endogenous heart regeneration-insights from adult zebrafish and neonatal mice
Nicole Rubin et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2016)
Reverse Genetics in Zebrafish: Mutants, Morphants, and Moving Forward
Nathan D. Lawson
TRENDS IN CELL BIOLOGY (2016)
Mixtures, Metabolites, and Mechanisms: Understanding Toxicology Using Zebrafish
Joshua T. Gamse et al.
ZEBRAFISH (2016)
Human pancreatic beta-like cells converted from fibroblasts
Saiyong Zhu et al.
NATURE COMMUNICATIONS (2016)
Genome-wide screening identifies a KCNIP1 copy number variant as a genetic predictor for atrial fibrillation
Chia-Ti Tsai et al.
NATURE COMMUNICATIONS (2016)
A mutation in the atrial-specific myosin light chain gene (MYL4) causes familial atrial fibrillation
Nathan Orr et al.
NATURE COMMUNICATIONS (2016)
Probiotic treatment reduces appetite and glucose level in the zebrafish model
Silvia Falcinelli et al.
SCIENTIFIC REPORTS (2016)
FOXN3 Regulates Hepatic Glucose Utilization
Santhosh Karanth et al.
CELL REPORTS (2016)
Zebrafish Embryonic Lipidomic Analysis Reveals that the Yolk Cell Is Metabolically Active in Processing Lipid
Daniel Fraher et al.
CELL REPORTS (2016)
A Plasmid Set for Efficient Bacterial Artificial Chromosome (BAC) Transgenesis in Zebrafish
Fernando Fuentes et al.
G3-GENES GENOMES GENETICS (2016)
A conserved bacterial protein induces pancreatic beta cell expansion during zebrafish development
Jennifer Hampton Hill et al.
ELIFE (2016)
Critical role for adenosine receptor A2a in β-cell proliferation
Nadja Schulz et al.
MOLECULAR METABOLISM (2016)
Homology Directed Knockin of Point Mutations in the Zebrafish tardbp and fus Genes in ALS Using the CRISPR/Cas9 System
Gary Alan Barclay Armstrong et al.
PLOS ONE (2016)
miR-19b Regulates Ventricular Action Potential Duration in Zebrafish
Alexander Benz et al.
SCIENTIFIC REPORTS (2016)
Discovery of a potentially deleterious variant in TMEM87B in a patient with a hemizygous 2q13 microdeletion suggests a recessive condition characterized by congenital heart disease and restrictive cardiomyopathy
Hung-Chun Yu et al.
COLD SPRING HARBOR MOLECULAR CASE STUDIES (2016)
A modifier screen identifies DNAJB6 as a cardiomyopathy susceptibility gene
Yonghe Ding et al.
JCI INSIGHT (2016)
Advances in the Study of Heart Development and Disease Using Zebrafish
Daniel R. Brown et al.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE (2016)
Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR
Maximilian Haeussler et al.
GENOME BIOLOGY (2016)
Skeletal muscle insulin resistance in zebrafish induces alterations in β-cell number and glucose tolerance in an age- and diet-dependent manner
Lisette A. Maddison et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2015)
Targeting mitochondrial energy metabolism with TSPO ligands
Philipp Gut
BIOCHEMICAL SOCIETY TRANSACTIONS (2015)
Flexible and waterproof micro-sensors to uncover zebrafish circadian rhythms: The next generation of cardiac monitoring for drug screening
Xiaoxiao Zhang et al.
BIOSENSORS & BIOELECTRONICS (2015)
Microscopy-Based High-Content Screening
Michael Boutros et al.
CELL (2015)
Regulation of transcriptionally active genes via the catalytically inactive Cas9 in C-elegans and D-rerio
Lijiang Long et al.
CELL RESEARCH (2015)
Metabolic insights from zebrafish genetics, physiology, and chemical biology
Amnon Schlegel et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2015)
Loss of Function Mutations in NNT Are Associated With Left Ventricular Noncompaction
Matthew N. Bainbridge et al.
CIRCULATION-CARDIOVASCULAR GENETICS (2015)
Cardiac Transcriptome and Dilated Cardiomyopathy Genes in Zebrafish
Yu-Huan Shih et al.
CIRCULATION-CARDIOVASCULAR GENETICS (2015)
15 years of zebrafish chemical screening
Andrew J. Rennekamp et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2015)
Islet formation in mice and men: lessons for the generation of functional insulin-producing β-cells from human pluripotent stem cells
Gopika Nair et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2015)
Differential levels of Neurod establish zebrafish endocrine pancreas cell fates
Gokhan Dalgin et al.
DEVELOPMENTAL BIOLOGY (2015)
Nerves Regulate Cardiomyocyte Proliferation and Heart Regeneration
Ahmed I. Mahmoud et al.
DEVELOPMENTAL CELL (2015)
Making Sense of Anti-Sense Data
Didier Y. R. Stainier et al.
DEVELOPMENTAL CELL (2015)
Morpholinos: Antisense and Sensibility
Martin Blum et al.
DEVELOPMENTAL CELL (2015)
Chemokine-Guided Angiogenesis Directs Coronary Vasculature Formation in Zebrafish
Michael R. M. Harrison et al.
DEVELOPMENTAL CELL (2015)
Reverse Genetic Screening Reveals Poor Correlation between Morpholino-Induced and Mutant Phenotypes in Zebrafish
Fatma O. Kok et al.
DEVELOPMENTAL CELL (2015)
High-resolution analysis of central nervous system expression patterns in zebrafish Gal4 enhancer-trap lines
Hideo Otsuna et al.
DEVELOPMENTAL DYNAMICS (2015)
Ovarian senescence increases liver fibrosis in humans and zebrafish with steatosis
Elena Turola et al.
DISEASE MODELS & MECHANISMS (2015)
Apoc2 loss-of-function zebrafish mutant as a genetic model of hyperlipidemia
Chao Liu et al.
DISEASE MODELS & MECHANISMS (2015)
Phenotype-driven chemical screening in zebrafish for compounds that inhibit collective cell migration identifies multiple pathways potentially involved in metastatic invasion
Viviana E. Gallardo et al.
DISEASE MODELS & MECHANISMS (2015)
High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9
Gaurav K. Varshney et al.
GENOME RESEARCH (2015)
Mutations in TAX1BP3 Cause Dilated Cardiomyopathy with Septo-Optic Dysplasia
Eyal Reinstein et al.
HUMAN MUTATION (2015)
Intrinsic and extrinsic innervation of the heart in zebrafish (Danio rerio)
Matthew R. Stoyek et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2015)
A human laterality disorder caused by a homozygous deleterious mutation in MMP21
Zeev Perles et al.
JOURNAL OF MEDICAL GENETICS (2015)
Studying lipoprotein trafficking in zebrafish, the case of chylomicron retention disease
Amnon Schlegel
JOURNAL OF MOLECULAR MEDICINE-JMM (2015)
Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment
Pulin Li et al.
NATURE (2015)
New genetic loci link adipose and insulin biology to body fat distribution
Dmitry Shungin et al.
NATURE (2015)
Genetic compensation induced by deleterious mutations but not gene knockdowns
Andrea Rossi et al.
NATURE (2015)
Genetic association analyses highlight biological pathways underlying mitral valve prolapse
Christian Dina et al.
NATURE GENETICS (2015)
Rapid reverse genetic screening using CRISPR in zebrafish
Arish N. Shah et al.
NATURE METHODS (2015)
Zebrafish as tools for drug discovery
Calum A. MacRae et al.
NATURE REVIEWS DRUG DISCOVERY (2015)
Plexin D1 determines body fat distribution by regulating the type V collagen microenvironment in visceral adipose tissue
James E. N. Minchin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Myocardial NF-κB activation is essential for zebrafish heart regeneration
Ravi Karra et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Dynamics of zebrafish fin regeneration using a pulsed SILAC approach
Hendrik Nolte et al.
PROTEOMICS (2015)
Identification of a plant isoflavonoid that causes biliary atresia
Kristin Lorent et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
Ontogenetic Differences in Dietary Fat Influence Microbiota Assembly in the Zebrafish Gut
Sandi Wong et al.
MBIO (2015)
Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function
Parveen Sharma et al.
NATURE COMMUNICATIONS (2015)
Diabetic pdx1-mutant zebrafish show conserved responses to nutrient overload and anti-glycemic treatment
Robin A. Kimmel et al.
SCIENTIFIC REPORTS (2015)
Lactobacillus rhamnosus lowers zebrafish lipid content by changing gut microbiota and host transcription of genes involved in lipid metabolism
Silvia Falcinelli et al.
SCIENTIFIC REPORTS (2015)
PTPMT1 Inhibition Lowers Glucose through Succinate Dehydrogenase Phosphorylation
Anjali K. Nath et al.
CELL REPORTS (2015)
An In Vivo Chemical Genetic Screen Identifies Phosphodiesterase 4 as a Pharmacological Target for Hedgehog Signaling Inhibition
Charles H. Williams et al.
CELL REPORTS (2015)
Developmental Alterations in Heart Biomechanics and Skeletal Muscle Function in Desmin Mutants Suggest an Early Pathological Root for Desminopathies
Caroline Ramspacher et al.
CELL REPORTS (2015)
A Multifunctional Mutagenesis System for Analysis of Gene Function in Zebrafish
Helen Ngoc Bao Quach et al.
G3-GENES GENOMES GENETICS (2015)
Loss of Function Mutations in NNT Are Associated With Left Ventricular Noncompaction
Matthew N. Bainbridge et al.
CIRCULATION-CARDIOVASCULAR GENETICS (2015)
Cardiac Transcriptome and Dilated Cardiomyopathy Genes in Zebrafish
Yu-Huan Shih et al.
CIRCULATION-CARDIOVASCULAR GENETICS (2015)
The hormonal peptide Elabela guides angioblasts to the midline during vasculogenesis
Christian S. M. Helker et al.
ELIFE (2015)
Mitochondrial Ca2+ uptake by the voltage-dependent anion channel 2 regulates cardiac rhythmicity
Hirohito Shimizu et al.
ELIFE (2015)
RIPOSTE: a framework for improving the design and analysis of laboratory-based research
Nicholas G. D. Masca et al.
ELIFE (2015)
Nrg1 is an injury-induced cardiomyocyte mitogen for the endogenous heart regeneration program in zebrafish
Matthew Gemberling et al.
ELIFE (2015)
An internal promoter underlies the difference in disease severity between Nand C-terminal truncation mutations of Titin in zebrafish
Jun Zou et al.
ELIFE (2015)
Tip cell-specific requirement for an atypical Gpr124-and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis
Benoit Vanhollebeke et al.
ELIFE (2015)
First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass
Guangliang Wang et al.
ELIFE (2015)
Testing Tuberculosis Drug Efficacy in a Zebrafish High-Throughput Translational Medicine Screen
Anita Ordas et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2015)
Long-Term Hyperphagia and Caloric Restriction Caused by Low- or High-Density Husbandry Have Differential Effects on Zebrafish Postembryonic Development, Somatic Growth, Fat Accumulation and Reproduction
Sandra Leibold et al.
PLOS ONE (2015)
A Post-Developmental Genetic Screen for Zebrafish Models of Inherited Liver Disease
Seok-Hyung Kim et al.
PLOS ONE (2015)
Advanced Echocardiography in Adult Zebrafish Reveals Delayed Recovery of Heart Function after Myocardial Cryoinjury
Selina J. Hein et al.
PLOS ONE (2015)
klf2ash317 Mutant Zebrafish Do Not Recapitulate Morpholino-Induced Vascular and Haematopoietic Phenotypes
Peter Novodvorsky et al.
PLOS ONE (2015)
Precise in-frame integration of exogenous DNA mediated by CRISPR/Cas9 system in zebrafish
Yu Hisano et al.
SCIENTIFIC REPORTS (2015)
Contributions of adipose tissue architectural and tensile properties toward defining healthy and unhealthy obesity
Denise E. Lackey et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2014)
Compound heterozygosity deteriorates phenotypes of hypertrophic cardiomyopathy with founder MYBPC3 mutation: evidence from patients and zebrafish models
Akihiko Hodatsu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2014)
The Increasing Urgency for Standards in Basic Biologic Research
Leonard P. Freedman et al.
CANCER RESEARCH (2014)
Heme Oxygenase-1 Drives Metaflammation and Insulin Resistance in Mouse and Man
Alexander Jais et al.
CELL (2014)
Genome-wide RNA Tomography in the Zebrafish Embryo
Jan Philipp Junker et al.
CELL (2014)
Development and Applications of CRISPR-Cas9 for Genome Engineering
Patrick D. Hsu et al.
CELL (2014)
Adipocyte Inflammation Is Essential for Healthy Adipose Tissue Expansion and Remodeling
Ingrid Wernstedt Asterholm et al.
CELL METABOLISM (2014)
Translational Research: The Path for Bringing Discovery to Patients
Leonard Zon
CELL STEM CELL (2014)
Actin Binding GFP Allows 4D In Vivo Imaging of Myofilament Dynamics in the Zebrafish Heart and the Identification of Erbb2 Signaling as a Remodeling Factor of Myofibril Architecture
Sven Reischauer et al.
CIRCULATION RESEARCH (2014)
High-resolution imaging of cardiomyocyte behavior reveals two distinct steps in ventricular trabeculation
David W. Staudt et al.
DEVELOPMENT (2014)
Out with the old, in with the new: reassessing morpholino knockdowns in light of genome editing technology
Stefan Schulte-Merker et al.
DEVELOPMENT (2014)
Precise and efficient genome editing in zebrafish using the CRISPR/Cas9 system
Uwe Irion et al.
DEVELOPMENT (2014)
Noonan and LEOPARD syndrome Shp2 variants induce heart displacement defects in zebrafish
Monica Bonetti et al.
DEVELOPMENT (2014)
Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain-mediated cardiotoxicity
Jian Guan et al.
EMBO MOLECULAR MEDICINE (2014)
Fructose Leads to Hepatic Steatosis in Zebrafish That Is Reversed by Mechanistic Target of Rapamycin (mTOR) Inhibition
Valerie Sapp et al.
HEPATOLOGY (2014)
RING Finger Protein RNF207, a Novel Regulator of Cardiac Excitation
Karim Roder et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia
Alejandro Gutierrez et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Hyperinsulinemia induces insulin resistance and immune suppression via Ptpn6/Shp1 in zebrafish
Ruben Marin-Juez et al.
JOURNAL OF ENDOCRINOLOGY (2014)
Thyroid hormone regulates cardiac performance during cold acclimation in zebrafish (Danio rerio)
Alexander G. Little et al.
JOURNAL OF EXPERIMENTAL BIOLOGY (2014)
Lxr-driven enterocyte lipid droplet formation delays transport of ingested lipids
Lourdes Cruz-Garcia et al.
JOURNAL OF LIPID RESEARCH (2014)
PZR Coordinates Shp2 Noonan and LEOPARD Syndrome Signaling in Zebrafish and Mice
Jeroen Paardekooper Overman et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
mTORC1 controls the adaptive transition of quiescent stem cells from G0 to GAlert
Joseph T. Rodgers et al.
NATURE (2014)
CRISPR-Cas systems for editing, regulating and targeting genomes
Jeffry D. Sander et al.
NATURE BIOTECHNOLOGY (2014)
Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects
Bin Shen et al.
NATURE METHODS (2014)
Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics
Alicia Lundby et al.
NATURE METHODS (2014)
High-resolution reconstruction of the beating zebrafish heart
Michaela Mickoleit et al.
NATURE METHODS (2014)
The discovery of first-in-class drugs: origins and evolution
Joerg Eder et al.
NATURE REVIEWS DRUG DISCOVERY (2014)
Generation of knockout mice using engineered nucleases
Young Hoon Sung et al.
METHODS (2014)
CRISPR/Cas9 and TALEN-mediated knock-in approaches in zebrafish
Thomas O. Auer et al.
METHODS (2014)
The Serine-Threonine Protein Kinase PAK4 Is Dispensable in Zebrafish: Identification of a Morpholino-Generated Pseudophenotype
Sheran H. W. Law et al.
PLOS ONE (2014)
Whole Organism High Content Screening Identifies Stimulators of Pancreatic Beta-Cell Proliferation
Naoki Tsuji et al.
PLOS ONE (2014)
The new frontier of genome engineering with CRISPR-Cas9
Jennifer A. Doudna et al.
SCIENCE (2014)
Visnagin protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase
Yan Liu et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
Identification of a New Modulator of the Intercalated Disc in a Zebrafish Model of Arrhythmogenic Cardiomyopathy
Angeliki Asimaki et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
Inhibition of poly-ADP ribose polymerase enzyme activity prevents hyperglycemia-induced impairment of angiogenesis during wound healing
Michael P. Sarras et al.
WOUND REPAIR AND REGENERATION (2014)
Targeted Laser Ablation of the Zebrafish Larval Heart Induces Models of Heart Block, Valvular Regurgitation, and Outflow Tract Obstruction
Gianfranco Matrone et al.
ZEBRAFISH (2014)
A Streamlined CRISPR Pipeline to Reliably Generate Zebrafish Frameshifting Alleles
Jared Coffin Talbot et al.
ZEBRAFISH (2014)
Optical assessment of the cardiac rhythm of contracting cardiomyocytes in vitro and a pulsating heart in vivo for pharmacological screening
Yu-Cheng Lai et al.
BIOMEDICAL OPTICS EXPRESS (2014)
An Efficient Genotyping Method for Genome-modified Animals and Human Cells Generated with CRISPR/Cas9 System
Xiaoxiao Zhu et al.
SCIENTIFIC REPORTS (2014)
S-Nitrosothiol Signaling Regulates Liver Development and Improves Outcome following Toxic Liver Injury
Andrew G. Cox et al.
CELL REPORTS (2014)
Recovery of Adult Zebrafish Hearts for High-throughput Applications
Rima Arnaout et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2014)
Prioritizing causal disease genes using unbiased genomic features
Rahul C. Deo et al.
GENOME BIOLOGY (2014)
Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCDC65 Defects as Causing Primary Ciliary Dyskinesia
Christina Austin-Tse et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
Gain-of-Function Mutations in RIT1 Cause Noonan Syndrome, a RAS/MAPK Pathway Syndrome
Yoko Aoki et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
BMP9 Mutations Cause a Vascular-Anomaly Syndrome with Phenotypic Overlap with Hereditary Hemorrhagic Telangiectasia
Whitney L. Wooderchak-Donahue et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
Human amyloidogenic light chain proteins result in cardiac dysfunction, cell death, and early mortality in zebrafish
Shikha Mishra et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2013)
Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation
Corey Cutler et al.
BLOOD (2013)
Rejuvenating SIRT1 Activators
Philipp Gut et al.
CELL METABOLISM (2013)
Trapping Cardiac Recessive Mutants via Expression-Based Insertional Mutagenesis Screening
Yonghe Ding et al.
CIRCULATION RESEARCH (2013)
Metabolic Regulation of Cellular Plasticity in the Pancreas
Nikolay Ninov et al.
CURRENT BIOLOGY (2013)
The zebrafish common cardinal veins develop by a novel mechanism: lumen ensheathment
Christian S. M. Helker et al.
DEVELOPMENT (2013)
Rapid identification of kidney cyst mutations by whole exome sequencing in zebrafish
Sean Ryan et al.
DEVELOPMENT (2013)
Efficient CRISPR/Cas9 genome editing with low off-target effects in zebrafish
Alexander Hruscha et al.
DEVELOPMENT (2013)
Real-time in vivo monitoring of circadian E-box enhancer activity: A robust and sensitive zebrafish reporter line for developmental, chemical and neural biology of the circadian clock
Meltem Weger et al.
DEVELOPMENTAL BIOLOGY (2013)
Zebrafish tbx5 Paralogs Demonstrate Independent Essential Requirements in Cardiac and Pectoral Fin Development
Lindsay E. Parrie et al.
DEVELOPMENTAL DYNAMICS (2013)
Polyunsaturated fatty acyl-coenzyme As are inhibitors of cholesterol biosynthesis in zebrafish and mice
Santhosh Karanth et al.
DISEASE MODELS & MECHANISMS (2013)
The emerging use of zebrafish to model metabolic disease
Asha Seth et al.
DISEASE MODELS & MECHANISMS (2013)
Cellular dynamics in the muscle satellite cell niche
C. Florian Bentzinger et al.
EMBO REPORTS (2013)
Dwarfism and Increased Adiposity in the gh1 Mutant Zebrafish vizzini
Sarah K. McMenamin et al.
ENDOCRINOLOGY (2013)
RNA-seq-based mapping and candidate identification of mutations from forward genetic screens
Adam C. Miller et al.
GENOME RESEARCH (2013)
Homeostatic Generation of Reactive Oxygen Species Protects the Zebrafish Liver From Steatosis
Justin M. Nussbaum et al.
HEPATOLOGY (2013)
Assessing the impact of thermal acclimation on physiological condition in the zebrafish model
Lucia Vergauwen et al.
JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY (2013)
The piggyBac Transposon Displays Local and Distant Reintegration Preferences and Can Cause Mutations at Noncanonical Integration Sites
Meng Amy Li et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
Nanog, Pou5f1 and SoxB1 activate zygotic gene expression during the maternal-to-zygotic transition
Miler T. Lee et al.
NATURE (2013)
The nexus of chromatin regulation and intermediary metabolism
Philipp Gut et al.
NATURE (2013)
A systematic genome-wide analysis of zebrafish protein-coding gene function
Ross N. W. Kettleborough et al.
NATURE (2013)
The zebrafish reference genome sequence and its relationship to the human genome
Kerstin Howe et al.
NATURE (2013)
Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism
Philipp Gut et al.
NATURE CHEMICAL BIOLOGY (2013)
The why and how of phenotypic small-molecule screens
Ulrike S. Eggert
NATURE CHEMICAL BIOLOGY (2013)
Cas9 as a versatile tool for engineering biology
Prashant Mali et al.
NATURE METHODS (2013)
The global NAFLD epidemic
Rohit Loomba et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2013)
Adult teleost heart expresses two distinct troponin C paralogs: cardiac TnC and a novel and teleost-specific ssTnC in a chamber- and temperature-dependent manner
Christine E. Genge et al.
PHYSIOLOGICAL GENOMICS (2013)
Efficient multiplex biallelic zebrafish genome editing using a CRISPR nuclease system
Li-En Jao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Imaging Beta Cell Regeneration and Interactions with Islet Vasculature in Transparent Adult Zebrafish
Larry G. Moss et al.
ZEBRAFISH (2013)
Dietary Protein Source Influence on Body Size and Composition in Growing Zebrafish
Daniel L. Smith et al.
ZEBRAFISH (2013)
In Silico Molecular Comparisons of C-elegans and Mammalian Pharmacology Identify Distinct Targets That Regulate Feeding
George A. Lemieux et al.
PLOS BIOLOGY (2013)
A simple strategy for heritable chromosomal deletions in zebrafish via the combinatorial action of targeting nucleases
Shimin Lim et al.
GENOME BIOLOGY (2013)
Gavaging Adult Zebrafish
Chereen Collymore et al.
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2013)
A Chemical Screening System for Glucocorticoid Stress Hormone Signaling in an Intact Vertebrate
Benjamin D. Weger et al.
ACS CHEMICAL BIOLOGY (2012)
Uncovering the Molecular and Cellular Mechanisms of Heart Development Using the Zebrafish
David Staudt et al.
ANNUAL REVIEW OF GENETICS, VOL 46 (2012)
Systems Genetics of Metabolism: The Use of the BXD Murine Reference Panel for Multiscalar Integration of Traits
Penelope A. Andreux et al.
CELL (2012)
Adenosine Signaling Promotes Regeneration of Pancreatic β Cells In Vivo
Olov Andersson et al.
CELL METABOLISM (2012)
Metabolic Disease Drug Discovery - Hitting the Target Is Easier Said Than Done
David E. Moller
CELL METABOLISM (2012)
Studying non-alcoholic fatty liver disease with zebrafish: a confluence of optics, genetics, and physiology
Amnon Schlegel
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
Different levels of Notch signaling regulate quiescence, renewal and differentiation in pancreatic endocrine progenitors
Nikolay Ninov et al.
DEVELOPMENT (2012)
Zebrafish sox9b is crucial for hepatopancreatic duct development and pancreatic endocrine cell regeneration
Isabelle Manfroid et al.
DEVELOPMENTAL BIOLOGY (2012)
Mutation of zebrafish Snapc4 is associated with loss of the intrahepatic biliary network
Madeline Schaub et al.
DEVELOPMENTAL BIOLOGY (2012)
Transgenic zebrafish illuminate the dynamics of thyroid morphogenesis and its relationship to cardiovascular development
Robert Opitz et al.
DEVELOPMENTAL BIOLOGY (2012)
Voltage-gated calcium channel CACNB2 (β2.1) protein is required in the heart for control of cell proliferation and heart tube integrity
Yelena Chernyavskaya et al.
DEVELOPMENTAL DYNAMICS (2012)
Nutrient Excess Stimulates β-Cell Neogenesis in Zebrafish
Lisette A. Maddison et al.
DIABETES (2012)
Heritable Transmission of Diabetic Metabolic Memory in Zebrafish Correlates With DNA Hypomethylation and Aberrant Gene Expression
Ansgar S. Olsen et al.
DIABETES (2012)
α-Actinin2 is required for the lateral alignment of Z discs and ventricular chamber enlargement during zebrafish cardiogenesis
Jingchun Yang et al.
FASEB JOURNAL (2012)
Emerging applications for zebrafish as a model organism to study oxidative mechanisms and their roles in inflammation and vascular accumulation of oxidized lipids
Longhou Fang et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
A monocarboxylate transporter required for hepatocyte secretion of ketone bodies during fasting
Sarah E. Hugo et al.
GENES & DEVELOPMENT (2012)
Efficient Mapping and Cloning of Mutations in Zebrafish by Low-Coverage Whole-Genome Sequencing
Margot E. Bowen et al.
GENETICS (2012)
Mutation mapping and identification by whole-genome sequencing
Ignaty Leshchiner et al.
GENOME RESEARCH (2012)
The basic helix-loop-helix transcription factor, heart and neural crest derivatives expressed transcript 2, marks hepatic stellate cells in zebrafish: Analysis of stellate cell entry into the developing liver
Chunyue Yin et al.
HEPATOLOGY (2012)
Loss of plakophilin 2 disrupts heart development in zebrafish
Miriam A. Moriarty et al.
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY (2012)
Validation of visualized transgenic zebrafish as a high throughput model to assay bradycardia related cardio toxicity risk candidates
Dingsheng Wen et al.
JOURNAL OF APPLIED TOXICOLOGY (2012)
Essential roles of zebrafish bmp2a, fgf10, and fgf24 in the specification of the ventral pancreas
Francois Naye et al.
MOLECULAR BIOLOGY OF THE CELL (2012)
Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010
Christopher J. L. Murray et al.
LANCET (2012)
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010
Theo Vos et al.
LANCET (2012)
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010
Rafael Lozano et al.
LANCET (2012)
In vivo genome editing using a high-efficiency TALEN system
Victoria M. Bedell et al.
NATURE (2012)
Clonally dominant cardiomyocytes direct heart morphogenesis
Vikas Gupta et al.
NATURE (2012)
Raise standards for preclinical cancer research
C. Glenn Begley et al.
NATURE (2012)
RNA-guided genetic silencing systems in bacteria and archaea
Blake Wiedenheft et al.
NATURE (2012)
FLASH assembly of TALENs for high-throughput genome editing
Deepak Reyon et al.
NATURE BIOTECHNOLOGY (2012)
Chemical informatics and target identification in a zebrafish phenotypic screen
Christian Laggner et al.
NATURE CHEMICAL BIOLOGY (2012)
The many faces of insulin-like peptide signalling in the brain
Ana M. Fernandez et al.
NATURE REVIEWS NEUROSCIENCE (2012)
TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction
Erin L. Doyle et al.
NUCLEIC ACIDS RESEARCH (2012)
Overexpression of Akt1 Enhances Adipogenesis and Leads to Lipoma Formation in Zebrafish
Che-Yu Chu et al.
PLOS ONE (2012)
Behavioral barcoding in the cloud: embracing data-intensive digital phenotyping in neuropharmacology
David Kokel et al.
TRENDS IN BIOTECHNOLOGY (2012)
Simple Methods for Generating and Detecting Locus-Specific Mutations Induced with TALENs in the Zebrafish Genome
Timothy J. Dahlem et al.
PLOS GENETICS (2012)
Ezetimibe and Simvastatin Reduce Cholesterol Levels in Zebrafish Larvae Fed a High-Cholesterol Diet
Ji Sun Baek et al.
CHOLESTEROL (2012)
Functions of the Wnt/β-catenin pathway in an anemia-induced zebrafish model of cardiomyopathy are location dependent
Tiffany Hoage et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Bisphenol A induces otolith malformations during vertebrate embryogenesis
Yann Gibert et al.
BMC DEVELOPMENTAL BIOLOGY (2011)
Novel Chemical Suppressors of Long QT Syndrome Identified by an In Vivo Functional Screen
David S. Peal et al.
CIRCULATION (2011)
Haploinsufficiency of Target of Rapamycin Attenuates Cardiomyopathies in Adult Zebrafish
Yonghe Ding et al.
CIRCULATION RESEARCH (2011)
The regenerative capacity of zebrafish reverses cardiac failure caused by genetic cardiomyocyte depletion
Jinhu Wang et al.
DEVELOPMENT (2011)
Rapid BAC selection for tol2-mediated transgenesis in zebrafish
Jeroen Bussmann et al.
DEVELOPMENT (2011)
Mef2cb regulates late myocardial cell addition from a second heart field-like population of progenitors in zebrafish
Savo Lazic et al.
DEVELOPMENTAL BIOLOGY (2011)
Retinoic Acid Production by Endocardium and Epicardium Is an Injury Response Essential for Zebrafish Heart Regeneration
Kazu Kikuchi et al.
DEVELOPMENTAL CELL (2011)
Zebrafish model of tuberous sclerosis complex reveals cell-autonomous and non-cell-autonomous functions of mutant tuberin
Seok-Hyung Kim et al.
DISEASE MODELS & MECHANISMS (2011)
Human cardiomyopathy mutations induce myocyte hyperplasia and activate hypertrophic pathways during cardiogenesis in zebrafish
Jason R. Becker et al.
DISEASE MODELS & MECHANISMS (2011)
Dynamic glucoregulation and mammalian-like responses to metabolic and developmental disruption in zebrafish
Agata Jurczyk et al.
GENERAL AND COMPARATIVE ENDOCRINOLOGY (2011)
A versatile gene trap to visualize and interrogate the function of the vertebrate proteome
Le A. Trinh et al.
GENES & DEVELOPMENT (2011)
In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish
Longhou Fang et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Adipose tissue remodeling and obesity
Kai Sun et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
DHODH modulates transcriptional elongation in the neural crest and melanoma
Richard Mark White et al.
NATURE (2011)
A TALE nuclease architecture for efficient genome editing
Jeffrey C. Miller et al.
NATURE BIOTECHNOLOGY (2011)
Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA)
Jeffry D. Sander et al.
NATURE METHODS (2011)
In vivo protein trapping produces a functional expression codex of the vertebrate proteome
Karl J. Clark et al.
NATURE METHODS (2011)
How were new medicines discovered?
David C. Swinney et al.
NATURE REVIEWS DRUG DISCOVERY (2011)
Molecular control of endothelial cell behaviour during blood vessel morphogenesis
Shane P. Herbert et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)
Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
Tomas Cermak et al.
NUCLEIC ACIDS RESEARCH (2011)
A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity
Claudio Mussolino et al.
NUCLEIC ACIDS RESEARCH (2011)
A High-Throughput Screen for Tuberculosis Progression
Ralph Carvalho et al.
PLOS ONE (2011)
The serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish
Yme U. van der Velden et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Chemical screen identifies FDA-approved drugs and target pathways that induce precocious pancreatic endocrine differentiation
Meritxell Rovira et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Human Fatty Liver Disease: Old Questions and New Insights
Jonathan C. Cohen et al.
SCIENCE (2011)
Transient Regenerative Potential of the Neonatal Mouse Heart
Enzo R. Porrello et al.
SCIENCE (2011)
Enhancing the Efficiency of N-Ethyl-N-Nitrosourea-Induced Mutagenesis in the Zebrafish
Nicolas Rohner et al.
ZEBRAFISH (2011)
Multifactorial Origins of Heart and Gut Defects in nipbl-Deficient Zebrafish, a Model of Cornelia de Lange Syndrome
Akihiko Muto et al.
PLOS BIOLOGY (2011)
Large Scale Zebrafish-Based In vivo Small Molecule Screen
Jijun Hao et al.
Jove-Journal of Visualized Experiments (2011)
Electrocardiogram Signals to Assess Zebrafih Heart Regeneration: Implication of Long QT Intervals
Fei Yu et al.
ANNALS OF BIOMEDICAL ENGINEERING (2010)
Long-term warm or cold acclimation elicits a specific transcriptional response and affects energy metabolism in zebrafish
Lucia Vergauwen et al.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY (2010)
A dual role for ErbB2 signaling in cardiac trabeculation
Jiandong Liu et al.
DEVELOPMENT (2010)
Distinct Troponin C Isoform Requirements in Cardiac and Skeletal Muscle
Vanessa M. Sogah et al.
DEVELOPMENTAL DYNAMICS (2010)
White Adipose Tissue Development in Zebrafish Is Regulated by Both Developmental Time and Fish Size
Dru Imrie et al.
DEVELOPMENTAL DYNAMICS (2010)
Predominant cone photoreceptor dysfunction in a hyperglycaemic model of non-proliferative diabetic retinopathy
Yolanda Alvarez et al.
DISEASE MODELS & MECHANISMS (2010)
Oxidized Cholesteryl Esters and Phospholipids in Zebrafish Larvae Fed a High Cholesterol Diet MACROPHAGE BINDING AND ACTIVATION
Longhou Fang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Ang2/Fat-Free Is a Conserved Subunit of the Golgi-associated Retrograde Protein Complex
F. Javier Perez-Victoria et al.
MOLECULAR BIOLOGY OF THE CELL (2010)
Primary contribution to zebrafish heart regeneration by gata4+ cardiomyocytes
Kazu Kikuchi et al.
NATURE (2010)
Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation
Chris Jopling et al.
NATURE (2010)
Rapid behavior-based identification of neuroactive small molecules in the zebrafish
David Kokel et al.
NATURE CHEMICAL BIOLOGY (2010)
High-throughput in vivo vertebrate screening
Carlos Pardo-Martin et al.
NATURE METHODS (2010)
The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome
Jung Sub Lim et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2010)
Advances in understanding tissue regenerative capacity and mechanisms in animals
Kenneth D. Poss
NATURE REVIEWS GENETICS (2010)
Identification of Novel Inhibitors of Dietary Lipid Absorption Using Zebrafish
Justin D. Clifton et al.
PLOS ONE (2010)
Suppression of Alk8-mediated Bmp signaling cell-autonomously induces pancreatic β-cells in zebrafish
Won-Suk Chung et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury
Trista E. North et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Cardiac conduction is required to preserve cardiac chamber morphology
Neil C. Chi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Optogenetic Control of Cardiac Function
Aristides B. Arrenberg et al.
SCIENCE (2010)
Creation of a Bacterial Cell Controlled by a Chemically Synthesized Genome
Daniel G. Gibson et al.
SCIENCE (2010)
Identification of a Primary Target of Thalidomide Teratogenicity
Takumi Ito et al.
SCIENCE (2010)
Blood Sugar Measurement in Zebrafish Reveals Dynamics of Glucose Homeostasis
Stefani C. Eames et al.
ZEBRAFISH (2010)
Can Animal Models of Disease Reliably Inform Human Studies?
H. Bart van der Worp et al.
PLOS MEDICINE (2010)
Micro-Electrocardiograms to Study Post-Ventricular Amputation of Zebrafish Heart
Ping Sun et al.
ANNALS OF BIOMEDICAL ENGINEERING (2009)
Genome-wide analysis of Tol2 transposon reintegration in zebrafish
Igor Kondrychyn et al.
BMC GENOMICS (2009)
Drug-Sensitized Zebrafish Screen Identifies Multiple Genes, Including GINS3, as Regulators of Myocardial Repolarization
David J. Milan et al.
CIRCULATION (2009)
Vascular Lipid Accumulation, Lipoprotein Oxidation, and Macrophage Lipid Uptake in Hypercholesterolemic Zebrafish
Konstantin Stoletov et al.
CIRCULATION RESEARCH (2009)
Sarcomere Mutations in Cardiomyopathy With Left Ventricular Hypertrabeculation
Lisa M. Dellefave et al.
CIRCULATION-CARDIOVASCULAR GENETICS (2009)
TNFα-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish s-adenosylhomocysteine hydrolase
Randolph P. Matthews et al.
DEVELOPMENT (2009)
Selective plane illumination microscopy techniques in developmental biology
Jan Huisken et al.
DEVELOPMENT (2009)
Plakoglobin has both structural and signalling roles in zebrafish development
Eva D. Martin et al.
DEVELOPMENTAL BIOLOGY (2009)
Regeneration of the Pancreas in Adult Zebrafish
Jennifer B. Moss et al.
DIABETES (2009)
Differential tissue-specific distribution of transcripts for the duplicated fatty acid-binding protein 10 (fabp10) genes in embryos, larvae and adult zebrafish (Danio rerio)
Ananda B. Venkatachalam et al.
FEBS JOURNAL (2009)
Ontogeny and nutritional control of adipogenesis in zebrafish (Danio rerio)
Edward J. Flynn et al.
JOURNAL OF LIPID RESEARCH (2009)
Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy
David Hassel et al.
NATURE MEDICINE (2009)
Targeted mutagenesis in zebrafish using customized zinc-finger nucleases
Jonathan E. Foley et al.
NATURE PROTOCOLS (2009)
Notch-responsive cells initiate the secondary transition in larval zebrafish pancreas
Michael J. Parsons et al.
MECHANISMS OF DEVELOPMENT (2009)
Cardiac Hypertrophy Involves Both Myocyte Hypertrophy and Hyperplasia in Anemic Zebrafish
Xiaojing Sun et al.
PLOS ONE (2009)
Distinct populations of quiescent and proliferative pancreatic β-cells identified by HOTcre mediated labeling
Daniel Hesselson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Breaking the Code of DNA Binding Specificity of TAL-Type III Effectors
Jens Boch et al.
SCIENCE (2009)
Arterial-Venous Segregation by Selective Cell Sprouting: An Alternative Mode of Blood Vessel Formation
Shane P. Herbert et al.
SCIENCE (2009)
Growth and Survival of Zebrafish (Danio rerio) Fed Different Commercial and Laboratory Diets
Anthony J. Siccardi et al.
ZEBRAFISH (2009)
Semi-automated Optical Heartbeat Analysis of Small Hearts
Karen Ocorr et al.
Jove-Journal of Visualized Experiments (2009)
Functional and developmental analysis of the blood-brain barrier in zebrafish
Jae-Yeon Jeong et al.
BRAIN RESEARCH BULLETIN (2008)
Deficient zebrafish ether-a-go-go-related gene channel gating causes Short-QT syndrome in zebrafish reggae mutants
David Hassel et al.
CIRCULATION (2008)
Endothelial Signals Modulate Hepatocyte Apicobasal Polarization in Zebrafish
Takuya F. Sakaguchi et al.
CURRENT BIOLOGY (2008)
Intra-endodermal interactions are required for pancreatic β cell induction
Won-Suk Chung et al.
DEVELOPMENTAL CELL (2008)
Bmp2 Signaling Regulates the Hepatic versus Pancreatic Fate Decision
Won-Suk Chung et al.
DEVELOPMENTAL CELL (2008)
Graded levels of Ptf1a differentially regulate endocrine and exocrine fates in the developing pancreas
P. Duc Si Dong et al.
GENES & DEVELOPMENT (2008)
Rapid Open-Source engineering of customized zinc-finger nucleases for highly efficient gene modification
Morgan L. Maeder et al.
MOLECULAR CELL (2008)
Reprogramming pancreatic exocrine cells to β-cells
[Anonymous]
CLINICAL PHARMACOLOGY & THERAPEUTICS (2008)
Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases
Yannick Doyon et al.
NATURE BIOTECHNOLOGY (2008)
Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases
Xiangdong Meng et al.
NATURE BIOTECHNOLOGY (2008)
Methods for generating and colonizing gnotobiotic zebrafish
Linh N. Pham et al.
NATURE PROTOCOLS (2008)
How to create the vascular tree? (Latest) help from the zebrafish
Danila Baldessari et al.
PHARMACOLOGY & THERAPEUTICS (2008)
Genetic dissection of neural circuits by Tol2 transposon-mediated Gal4 gene and enhancer trapping in zebrafish
Kazuhide Asakawa et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
In vivo cardiac imaging of adult zebrafish using high frequency ultrasound (45-75 mhz)
Lei Sun et al.
ULTRASOUND IN MEDICINE AND BIOLOGY (2008)
Genetic and physiologic dissection of the vertebrate cardiac conduction system
Neil C. Chi et al.
PLOS BIOLOGY (2008)
In vivo reprogramming of adult pancreatic exocrine cells to β-cells
Qiao Zhou et al.
NATURE (2008)
Insertional mutagenesis by the Tol2 transposon-mediated enhancer trap approach generated mutations in two developmental genes: tcf7 and synembryn-like
Saori Nagayoshi et al.
DEVELOPMENT (2008)
Gata5 and Gata6 are functionally redundant in zebrafish for specification of cardiomyocytes
Audrey Holtzinger et al.
DEVELOPMENTAL BIOLOGY (2007)
Intestinal alkaline phosphatase detoxifies lipopolysaccharide and prevents inflammation in zebrafish in response to the gut microbiota
Jennifer M. Bates et al.
CELL HOST & MICROBE (2007)
Reciprocal endoderm-mesoderm interactions mediated by fgf24 and fgf10 govern pancreas development
Isabelle Manfroid et al.
DEVELOPMENT (2007)
Lessons from ''lower'' organisms: What worms, flies, and zebrafish can teach us about human energy metabolism
Amnon Schlegel et al.
PLOS GENETICS (2007)
The Tol2kit:: A multisite Gateway-based construction kit for Tol2 transposon transgenesis constructs
Kristen M. Kwan et al.
DEVELOPMENTAL DYNAMICS (2007)
SIRT1 controls endothelial angiogenic functions during vascular growth
Michael Potente et al.
GENES & DEVELOPMENT (2007)
Ligand activation of LXRβ reverses atherosclerosis and cellular cholesterol overload in mice lacking LXRα and apoE
Michelle N. Bradley et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Germline gain-of-function mutations in RAF1 cause Noonan syndrome
M. Abdur Razzaque et al.
NATURE GENETICS (2007)
Laminin-α4 and integrin-linked kinase mutations cause human cardiomyopathy via simultaneous defects in cardiomyocytes and endothelial cells
Ralph Knoell et al.
CIRCULATION (2007)
Zebrafish model for human long QT syndrome
Rima Arnaout et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Creation of a genetic model of obesity in a teleost
Youngsup Song et al.
FASEB JOURNAL (2007)
Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis
Trista E. North et al.
NATURE (2007)
Animal models of human disease: zebrafish swim into view
Graham J. Lieschke et al.
NATURE REVIEWS GENETICS (2007)
Conditional targeted cell ablation in zebrafish: A new tool for regeneration studies
Silvia Curado et al.
DEVELOPMENTAL DYNAMICS (2007)
Targeting neural circuitry in zebrafish using GAL4 enhancer trapping
Ethan K. Scott et al.
NATURE METHODS (2007)
Fgf10 regulates hepatopancreatic ductal system patterning and differentiation
P. Duc Si Dong et al.
NATURE GENETICS (2007)
Larval zebrafish as a model for glucose metabolism: expression of phosphoenolpyruvate carboxykinase as a marker for exposure to anti-diabetic compounds
B. Elo et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2007)
Targeted ablation of beta cells in the embryonic zebrafish pancreas using E-coli nitroreductase
Harshan Pisharath et al.
MECHANISMS OF DEVELOPMENT (2007)
A new time-scale for ray-finned fish evolution
Imogen A. Hurley et al.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2007)
Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries
Arndt F. Siekmann et al.
NATURE (2007)
Illuminating cardiac development: Advances in imaging add new dimensions to the utility of zebrafish genetics
Jeffrey J. Schoenebeck et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2007)
Microsomal triglyceride transfer protein is required for yolk lipid utilization and absorption of dietary lipids in zebrafish larvae
Amnon Schlegel et al.
BIOCHEMISTRY (2006)
Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells
Kevin A. D'Amour et al.
NATURE BIOTECHNOLOGY (2006)
Reciprocal gut microbiota transplants from zebrafish and mice to germ-free recipients reveal host habitat selection
John F. Rawls et al.
CELL (2006)
The bHLH transcription factor hand2 is essential for noradrenergic differentiation of sympathetic neurons
Marsha E. Lucas et al.
DEVELOPMENT (2006)
Functional dissection of the Tol2 transposable element identified the minimal cis-sequence and a highly repetitive sequence in the subterminal region essential for transposition
Akihiro Urasaki et al.
GENETICS (2006)
A clinical drug library screen identifies astemizole as an antimalarial agent
Curtis R. Chong et al.
NATURE CHEMICAL BIOLOGY (2006)
Gene-breaking transposon mutagenesis reveals an essential role for histone H2afza in zebrafish larval development
Sridhar Sivasubbu et al.
MECHANISMS OF DEVELOPMENT (2006)
In vivo recording of adult zebrafish electrocardiogram and assessment of drug-induced QT prolongation
David J. Milan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2006)
Zebrafish fat-free is required for intestinal lipid absorption and Golgi apparatus structure
SY Ho et al.
CELL METABOLISM (2006)
Notch1b and neuregulin are required for specification of central cardiac conduction tissue
DJ Milan et al.
DEVELOPMENT (2006)
Calcium extrusion is critical for cardiac morphogenesis and rhythm in embryonic zebrafish hearts
AM Ebert et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Mutation in sodium-calcium exchanger 1 (NCX1) causes cardiac fibrillation in zebrafish
AD Langenbacher et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development
D Beis et al.
DEVELOPMENT (2005)
A genetic screen in zebrafish identifies the mutants vps18, nf2 and foie gras as models of liver disease
KC Sadler et al.
DEVELOPMENT (2005)
VEGF-PLCγ1 pathway controls cardiac contractility in the embryonic heart
W Rottbauer et al.
GENES & DEVELOPMENT (2005)
Mutation in the transcriptional coactivator EYA4 causes dilated cardiomyopathy and sensorineural hearing loss
J Schönberger et al.
NATURE GENETICS (2005)
In vivo drug discovery in the zebrafish
LI Zon et al.
NATURE REVIEWS DRUG DISCOVERY (2005)
Gnotobiotic zebrafish reveal evolutionarily conserved responses to the gut microbiota
JF Rawls et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
A zebrafish model for pyruvate dehydrogenase deficiency: Rescue of neurological dysfunction and embryonic lethality using a ketogenic diet
MR Taylor et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
TILLING - a high-throughput harvest for functional genomics
DL Stemple
NATURE REVIEWS GENETICS (2004)
Sudden death associated with short-QT syndrome linked to mutations in HERG
R Brugada et al.
CIRCULATION (2004)
Phylogenetic timing of the fish-specific genome duplication correlates with the diversification of teleost fish
S Hoegg et al.
JOURNAL OF MOLECULAR EVOLUTION (2004)
Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation
RT Peterson et al.
NATURE BIOTECHNOLOGY (2004)
Zebrafish embryos express an orthologue of HERG and are sensitive toward a range and are of QT-prolonging drugs inducing severe arrhythmia
U Langheinrich et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2003)
The Wnt/β-catenin pathway regulates cardiac valve formation
AFL Hurlstone et al.
NATURE (2003)
Regulation and mechanisms of mammalian double-strand break repair
K Valerie et al.
ONCOGENE (2003)
Formation of the digestive system in zebrafish. II. Pancreas morphogenesis
HA Field et al.
DEVELOPMENTAL BIOLOGY (2003)
Drugs that induce repolarization abnormalities cause bradycardia in zebrafish
DJ Milan et al.
CIRCULATION (2003)
Efficient target-selected mutagenesis in zebrafish
E Wienholds et al.
GENOME RESEARCH (2003)
From endoderm formation to liver and pancreas development in zebrafish
EA Ober et al.
MECHANISMS OF DEVELOPMENT (2003)
I-SceI meganuclease mediates highly efficient transgenesis in fish
V Thermes et al.
MECHANISMS OF DEVELOPMENT (2002)
Arteries and veins: Making a difference with zebrafish
ND Lawson et al.
NATURE REVIEWS GENETICS (2002)
Retinoic acid signaling is required for a critical early step in zebrafish pancreatic development
D Stafford et al.
CURRENT BIOLOGY (2002)
Cardiac troponin T is essential in sarcomere assembly and cardiac contractility
AJ Sehnert et al.
NATURE GENETICS (2002)
Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titin
XL Xu et al.
NATURE GENETICS (2002)
Vhnf1, the MODY5 and familial GCKD-associated gene, regulates regional specification of the zebrafish gut, pronephros, and hindbrain
ZX Sun et al.
GENES & DEVELOPMENT (2001)
The art and design of genetic screens: Zebrafish
EE Patton et al.
NATURE REVIEWS GENETICS (2001)
The slow mo mutation reduces pacemaker current and heart rate in adult zebrafish
KS Warren et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2001)
UDP-glucose dehydrogenase required for cardiac valve formation in zebrafish
EC Walsh et al.
SCIENCE (2001)
Genetic analysis of digestive physiology using fluorescent phospholipid reporters
SA Farber et al.
SCIENCE (2001)
Endocrine pancreas plasticity under physiological and pathological conditions
C Bernard-Kargar et al.
DIABETES (2001)
Identification of a functional transposase of the Tol2 element, an Ac-like element from the Japanese medaka fish, and its transposition in the zebrafish germ lineage
K Kawakami et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Effective targeted gene 'knockdown' in zebrafish
A Nasevicius et al.
NATURE GENETICS (2000)
Zebrafish dracula encodes ferrochelatase and its mutation provides a model for erythropoietic protoporphyria
S Childs et al.
CURRENT BIOLOGY (2000)
An inherited functional circadian clock in zebrafish embryos
F Delaunay et al.
SCIENCE (2000)
A sphingosine-1-phosphate receptor regulates cell migration during vertebrate heart development
E Kupperman et al.
NATURE (2000)
Zebrafish: a model system for the study of human disease
K Dooley et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2000)
Realizing the potential of zebrafish as a model for human disease
BA Barut et al.
PHYSIOLOGICAL GENOMICS (2000)
分享论文
