期刊
MINERVA GINECOLOGICA
卷 70, 期 4, 页码 432-435出版社
EDIZIONI MINERVA MEDICA
DOI: 10.23736/S0026-4784.18.04240-5
关键词
Ovary; Freezing; Fertility preservation; Transplantation; Thalassemia
资金
- UK Medical Research Council (MRC Grant) [G0801261, MR/K020501-1]
- MRC [G0801261] Funding Source: UKRI
Ovarian tissue removed from a 9-year-old girl suffering from thalassemia was kept deep-frozen for 14 years before being transplanted back to the now adult woman. Subsequently, she conceived following IVF treatment and delivered a healthy baby where the oocyte derived from the transplanted tissue. This is the first woman worldwide to have a baby where the ovarian tissue was frozen pre-pubertally and expand the therapeutic options for rare genetic diseases like thalassemia and girls who suffer from childhood cancer.
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