4.6 Article

PORCUPINE regulates development in response to temperature through alternative splicing

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NATURE PLANTS
卷 4, 期 8, 页码 534-539

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NATURE RESEARCH
DOI: 10.1038/s41477-018-0176-z

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资金

  1. DFG through the Sonderforschungsbereich 1101 (Collaborative Research Centre 1101) [SFB1101/1-C04]
  2. Knut and Alice Wallenberg Foundation [KAW 2016.0025]

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Recent findings suggest that alternative splicing has a critical role in controlling the responses of plants to temperature variations. However, alternative splicing factors in plants are largely uncharacterized. Here we establish the putative splice regulator, PORCUPINE (PCP), as temperature-specific regulator of development in Arabidopsis thaliana. Our findings point to the misregulation of WUSCHEL and CLAVATA3 as the possible cause for the meristem defects affecting the pcp-1 loss-of-function mutants at low temperatures.

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