期刊
PRECISION CLINICAL MEDICINE
卷 1, 期 2, 页码 65-74出版社
OXFORD UNIV PRESS
DOI: 10.1093/pcmedi/pby011
关键词
cancer; immune evasion; immunotherapy
资金
- National Institutes of Health [R01GM108661]
- National Natural Science Foundation of China [81572850]
Traditional cancer therapies include surgery, radiation, and chemotherapy, all of which are typically nonspecific approaches. Cancer immunotherapy is a type of cancer treatment that helps the immune system fight cancer. Cancer immunotherapy represents a standing example of precision medicine: immune checkpoint inhibitors precisely target the checkpoints; tumor infiltrating lymphocytes, TCR T cells, and CAR T cells precisely kill cancer cells through tumor antigen recognition; and cancer vaccines are made from patient-derived dendritic cells, tumor cell DNA, or RNA, or oncolytic viruses, thus offering a type of personalized medicine. This review will highlight up-to-date advancement in most, if not all, of the immunotherapy strategies.
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