3.9 Review

Recent updates on cancer immunotherapy

期刊

PRECISION CLINICAL MEDICINE
卷 1, 期 2, 页码 65-74

出版社

OXFORD UNIV PRESS
DOI: 10.1093/pcmedi/pby011

关键词

cancer; immune evasion; immunotherapy

资金

  1. National Institutes of Health [R01GM108661]
  2. National Natural Science Foundation of China [81572850]

向作者/读者索取更多资源

Traditional cancer therapies include surgery, radiation, and chemotherapy, all of which are typically nonspecific approaches. Cancer immunotherapy is a type of cancer treatment that helps the immune system fight cancer. Cancer immunotherapy represents a standing example of precision medicine: immune checkpoint inhibitors precisely target the checkpoints; tumor infiltrating lymphocytes, TCR T cells, and CAR T cells precisely kill cancer cells through tumor antigen recognition; and cancer vaccines are made from patient-derived dendritic cells, tumor cell DNA, or RNA, or oncolytic viruses, thus offering a type of personalized medicine. This review will highlight up-to-date advancement in most, if not all, of the immunotherapy strategies.

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