期刊
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
卷 193, 期 5, 页码 306-316出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/10426507.2017.1417296
关键词
Multicomponent reaction; 2-amino-4H-chromen-4-ylphosphonate derivatives; deep eutectic solvent; one-pot synthesis; green chemistry
资金
- Research Grant of Pukyoung National University
Synthesis of 2-amino-4H-chromen-4-ylphosphonate derivatives has been accomplished by the one-pot three-component reaction of salicylaldehyde, malononitrile/ethylcyanoacetate and dialkyl phosphites in the presence of reusable deep eutectic solvent (DES) under mild conditions. The advantages of this method are mild reaction conditions, simple work-up procedure, use of DES as a green solvent and an economical protocol for the preparation of important biologically active phosphorus-containing compounds. [GRAPHICS]
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