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Kathryn J. Ruddy et al.
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F. L. Opdam et al.
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L. K. Teh et al.
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In Hae Park et al.
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I. Sestak et al.
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Yusuke Nakamura et al.
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Christine M. Walko et al.
PHARMACOGENOMICS (2012)
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Matthew P. Goetz et al.
CLINICAL CANCER RESEARCH (2011)
Increasing Tamoxifen Dose in Breast Cancer Patients Based on CYP2D6 Genotypes and Endoxifen Levels: Effect on Active Metabolite Isomers and the Antiestrogenic Activity Score
M. F. Barginear et al.
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T. E. Muerdter et al.
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L. Madlensky et al.
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William J. Irvin et al.
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Hyung Seok Park et al.
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T. Ramon y Cajal et al.
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Kazuma Kiyotani et al.
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Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 10-year analysis of the ATAC trial
Jack Cuzick et al.
LANCET ONCOLOGY (2010)
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Jean E. Abraham et al.
BREAST CANCER RESEARCH (2010)
The CYP2D6*4 polymorphism affects breast cancer survival in tamoxifen users
Monique J. Bijl et al.
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Masatsugu Okishiro et al.
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William G. Newman et al.
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A. Gaedigk et al.
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Silvana Borges et al.
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SA Nowell et al.
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Z Desta et al.
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