期刊
PHARMACEUTICAL RESEARCH
卷 34, 期 8, 页码 1544-1550出版社
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s11095-017-2128-0
关键词
biomarkers; clinical uptake; diagnostic tests; personalized medicine
Pharmacogenetic testing aims to personalize drug therapy with a view to optimising drug efficacy and minimise toxicity. However, despite the potential benefits, pharmacogenetic testing is mostly confined to specialised medical areas, laboratories and centres. Widespread integration into routine clinical practice has been limited by a complex set of issues including regulatory and reimbursement frameworks, evidence of clinical utility and clinician perspectives, practices and education. Here we assess the current barriers to widespread clinical uptake and identify the key issue necessary to address to accelerate routine testing.
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