期刊
GENETICS
卷 210, 期 1, 页码 3-13出版社
GENETICS SOCIETY AMERICA
DOI: 10.1534/genetics.118.301084
关键词
Drosophila; Muller elements; synteny; chromosomal inversions
资金
- National Institute for General Medical Sciences at the National Institutes of Health [R01 GM-098478]
The concept of synteny, or conservation of genes on the same chromosome, traces its origins to the early days of Drosophila genetics. This discovery emerged from comparisons of linkage maps from different species of Drosophila with the goal of understanding the process of speciation. H. J. Muller published a landmark article entitled Bearings of the Drosophila work on systematics, where he synthesized genetic and physical map data and proposed a model of speciation and chromosomal gene content conservation. These models have withstood the test of time with the advent of molecular genetic analysis from protein to genome level variation. Muller's ideas provide a framework to begin to answer questions about the evolutionary forces that shape the structure of the genome.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据