期刊
PEDIATRIC SURGERY INTERNATIONAL
卷 34, 期 2, 页码 161-168出版社
SPRINGER
DOI: 10.1007/s00383-017-4184-2
关键词
Congenital diaphragmatic hernia; Magnetic resonance imaging; Fetal lung to liver signal intensity ratio; Pulmonary hypoplasia
We investigated the developmental changes in the unaffected contralateral lungs of patients with isolated left-sided congenital diaphragmatic hernia (CDH) using signal intensity ratios on prenatal magnetic resonance imaging (MRI) and determined whether these changes correlated with clinical outcomes. We performed 47 fetal MRI screens on 30 patients with isolated left-sided CDH. A cohort of 88 fetuses was selected as the control. We calculated the lung-to-liver signal intensity ratio (LLSIR) using region of interest analysis and compared LLSIR between the groups and between those in the CDH group with good and poor prognoses. In the control group, LLSIR increased as pregnancy progressed [regression line = 2.232 + 0.135 x (GW-23), r = 0.669]. In the CDH group, especially in the poor prognosis group, LLSIR did not significantly increase as pregnancy progressed [regression line for good prognosis = 1.827 + 0.092 x (gestational week-23), r = 0.733; regression line for poor prognosis = 1.731 + 0.025 x (gestational week-23), r = 0.634]. Fetal LLSIR on T2-weighted MRI is an accurate marker of fetal lung maturity that correlates with postnatal survival and can potentially be used as a prognostic parameter in CDH management.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据