期刊
EFSA JOURNAL
卷 16, 期 8, 页码 -出版社
WILEY
DOI: 10.2903/j.efsa.2018.5346
关键词
GMO; soybean (Glycinemax); MON87751; Cry1A; 105; Cry2Ab2; insect resistant; Regulation (EC) No 1829/2003
资金
- BBSRC [BBS/E/C/00004975, BB/L017768/1, BBS/E/W/0012843D] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BBS/E/C/00004158, BB/L017768/1, 1096616, BBS/E/C/00004975, BBS/E/W/0012843D] Funding Source: researchfish
Soybean MON87751 was developed through Agrobacterium tumefaciens-mediated transformation to provide protection certain specific lepidopteran pests by the expression of the Cry1A.105 and Cry2Ab2 proteins derived from Bacillus thuringiensis. The molecular characterisation data and bioinformatic analyses did not identify issues requiring assessment for food and feed safety. None of the compositional, agronomic and phenotypic differences identified between soybean MON87751 and the conventional counterpart required further assessment. The GMO Paneldid not identify safety concerns regarding the toxicity and allergenicity of the Cry1A.105 and Cry2Ab2 proteins as expressed in soybean MON87751, and found no evidence that the genetic modification might significantly change the overall allergenicity of soybean MON87751. The nutritional impact of soybean MON87751-derived food and feed is expected to be the same as those derived from the conventional counterpart and non-GM commercial reference varieties. The GMO Panelconcludes that soybean MON87751, as described in this application, is nutritionally equivalent to and as safe as the conventional counterpart and the non-GM soybean reference varieties tested, and no post-market monitoring of food and feed is considered necessary. In the case of accidental release of viable soybean MON87751 seeds into the environment, soybean MON87751 would not raise environmental safety concerns. The post-market environmental monitoring plan and reporting intervals are in line with the intended uses of soybean MON87751. In conclusion, soybean MON87751, as described in this application, is as safe as its conventional counterpart and the tested non-GM soybean reference varieties with respect to potential effects on human and animal health and the environment.
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