期刊
PARKINSONISM & RELATED DISORDERS
卷 37, 期 -, 页码 116-117出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.parkreldis.2017.01.013
关键词
Co-occurrence; Crohn's disease; LRRK2; Parkinson's disease
资金
- NIH/NINDS [P50 NS072187]
- Jaye F. and Betty F. Dyer Foundation
- Max Kade Foundation
- Mayo Clinic Center for Regenerative Medicine
- Allergan Medical Educational Grant
- Mayo Clinic Center for Individualized Medicine
- Mayo Clinic Neuroscience Focused Research Team/Cecilia and Dan Carmichael Family Foundation
- James C. and Sarah K. Kennedy Fund for Neurodegenerative Disease Research at Mayo Clinic in Florida
- Sol Goldman Charitable Trust
We retrospectively investigated the co-occurrence of Crohn's disease in a cohort of 876 patients with Parkinson's disease, based on the observation that LRRK2 is a shared genetic risk factor. We identified 2 patients with Crohn's disease; this number was consistent with the number of cases expected in the general population. (C) 2017 Elsevier Ltd. All rights reserved.
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