期刊
GENOME BIOLOGY
卷 19, 期 -, 页码 -出版社
BMC
DOI: 10.1186/s13059-018-1519-9
关键词
-
资金
- NIH [R35GM124820, R01HG009906, U01CA200060, R01HG007175, R01HG007354, R01ES024992, U24ES026699, U01HG009391, U54DK107977, R01HG006292, R01HL129132]
- Leukemia Research Foundation
- PhRMA Foundation
- Penn State CTSI
Here, we introduce the 3D Genome Browser, http://3dgenome.org , which allows users to conveniently explore both their own and over 300 publicly available chromatin interaction data of different types. We design a new binary data format for Hi-C data that reduces the file size by at least a magnitude and allows users to visualize chromatin interactions over millions of base pairs within seconds. Our browser provides multiple methods linking distal cis-regulatory elements with their potential target genes. Users can seamlessly integrate thousands of other omics data to gain a comprehensive view of both regulatory landscape and 3D genome structure.
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