期刊
THERAPEUTIC DELIVERY
卷 9, 期 8, 页码 593-604出版社
FUTURE SCI LTD
DOI: 10.4155/tde-2018-0025
关键词
alopecia; drug delivery; hair follicle; hair loss; nanocarrier; nanoparticles; skin
资金
- Coordination for Higher Education Personnel Improvement (CAPES)
- Research support foundation of the Federal District (FAPDF)
- National Council for the Research and Development (CNPq)
Alopecia is the partial or total reduction of hair in a specific area of the skin that affects millions of men and women worldwide. Most common approved treatments present inconvenient therapeutic regimes and serious adverse effects. In this scenario, nanoencapsulation has emerged as a relatively simple technology for improving the therapeutic outcome of this pathology, promoting a targeted drug delivery with enhanced local bioavailability, which could reduce the adverse effects. Herein, we present some recent studies involving the nanosystems developed for the pharmacological treatment of alopecia, highlighting how each system represents an improvement in relation to conventional drug products and the future perspectives of these new technologies in reaching the market.
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