期刊
OSTEOPOROSIS INTERNATIONAL
卷 28, 期 6, 页码 1765-1769出版社
SPRINGER LONDON LTD
DOI: 10.1007/s00198-017-3976-5
关键词
Fracture; Imminent; Osteoporosis; Treatment
资金
- Alexion
- Amgen
- Lilly
- UCB
- MSD
- PFIZER
The clinical significance of osteoporosis is in the occurrence of fractures and re-fractures. The main risk factor of sustaining a fracture is a previous one, but a recent fracture is a better fracture risk factor than fracture history. The role of the recency of fracture has been shown for both vertebral and non-vertebral fracture risk. This imminent risk is explained by both bone-related factors (underlying osteoporosis) and fall-related factors (including those related to postfracture care). Such a short-term increased risk has been shown also in patients initiating corticosteroids and in frail osteoporotic subjects with central nervous system (CNS) diseases or drugs targeting CNS, and thus a high risk of falls. Patients with an imminent (i.e. 2 years) risk of fracture or refracture should be identified in priority in order to receive an immediate treatment and a program of fall prevention.
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