期刊
ORGANOMETALLICS
卷 36, 期 13, 页码 2418-2423出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.organomet.7b00309
关键词
-
资金
- Science and Engineering Research Board, India
- CSIR
- UGC-INDIA
- IIT Bombay
Selective meta-C-H activation of arenes to date has met with a limited number of functionalizations. Expanding the horizon of meta-C-H functionalization, herein we disclose an unprecedented meta-silylation and -germanylation protocol by employing a simple nitrile-based directing template. Longer linkers between the target site and the directing template were successfully explored for meta-silylation (sp(2)-epsilon and sp(2)-zeta). Additionally, synthetic utility was demonstrated with several postsynthetic elaborations and with a formal synthesis of TAC101, a promising drug for the treatment of lung cancer.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据